P4510
聚-ε-Cbz-L-赖氨酸
mol wt 500-4,000
别名:
N6-[(phenylmethoxy)carbonyl]-L-lysine homopolymer
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关于此项目
form
powder
Quality Level
mol wt
500-4,000
color
white
storage temp.
−20°C
SMILES string
[N+H3][C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)[O-]
InChI
1S/C14H20N2O4/c15-12(13(17)18)8-4-5-9-16-14(19)20-10-11-6-2-1-3-7-11/h1-3,6-7,12H,4-5,8-10,15H2,(H,16,19)(H,17,18)/t12-/m0/s1
InChI key
CKGCFBNYQJDIGS-LBPRGKRZSA-N
Application
- 聚乙烯亚胺包被微球的转染技术。：该研究探讨了利用聚乙亚胺包被微球中的聚-e-苄氧羰基-L-赖氨酸来增强细胞转染的方法，结果表明这种方法提高了效率，并有可能应用于基因治疗（Manuel WS et al., 2001）。
- 由表面结合聚乙烯亚胺的生物可降解聚合物材料介导的细胞转染。：研究重点是用于细胞转染的生物可降解聚合物材料，包括聚乙二醇-苄氧羰基-L-赖氨酸对聚，强调了它们的生物可降解性和传递遗传物质的有效性（Zheng J et al., 2000）。
- 用聚（乳酸-共聚乙二醇）和聚（ε-CBZ-L-赖氨酸）的混合物生产表面带有氨基的微球并用于封装。：这篇论文讨论了利用聚乙二醇-苄氧羰基-L-赖氨酸的混合物制造带有表面氨基的微球，然后将其用于封装活性剂，并指出了其在给药系统中的应用（Zheng J et al., 1999）。
- 对聚（L-乳酸）材料进行改性，使其能与生物聚合物共价结合：应用于在附有胶原蛋白的泡沫中进行高密度三维细胞培养。：该研究探讨了用聚乙二醇-苄氧羰基-L-赖氨酸对聚（L-乳酸）材料进行改性，使其与生物聚合物共价结合，从而促进高密度三维细胞培养的应用（Zheng J et al., 1998）。
Analysis Note
电喷雾质谱法分子量
Other Notes
如需关于聚氨基酸的额外技术信息，请访问聚氨基酸FAQ资源。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
W S Manuel et al.
Journal of drug targeting, 9(1), 15-22 (2001-05-30)
Polyethyleneimine (PEI) can be used as a DNA delivery mechanism in cell culture and in vivo. Cells can be transfected by using surface-bound PEI, as well as by PEI/DNA microparticles. In the present experiments we extended these observations by preparing
Chimdiya Onwukwe et al.
Bioconjugate chemistry, 29(7), 2436-2447 (2018-07-03)
Bleeding from traumatic injury is the leading cause of death for young people across the world, but interventions are lacking. While many agents have shown promise in small animal models, translating the work to large animal models has been exceptionally
J Zheng et al.
Biotechnology progress, 15(4), 763-767 (1999-08-12)
Microspheres were formed from blends of the biodegradable polymer poly(DL-lactic-co-glycolic acid) (PLGA) together with poly(epsilon-CBZ-L-lysine) (PCBZL) by a double-emulsification/solvent evaporation technique. The size of the microspheres formed by this method was dependent both on the total concentration of the polymers
Qian Guo et al.
Journal of controlled release : official journal of the Controlled Release Society, 303, 117-129 (2019-04-27)
Brain metastases present mostly multifocal, infiltrative and co-opting growth with the blood-brain barrier (BBB) remaining intact. The BBB, as the barrier of drug delivery to such lesions, is the major cause of the failure of systemic drug therapy and needs
J Zheng et al.
Biotechnology progress, 16(2), 254-257 (2000-04-08)
Poly(epsilon-CBZ-L-lysine) can be mixed with biodegradable polymers such as poly(D,L-lactic-co-glycolic acid) or poly(L-lactic acid) and formed into films, foams, or microspheres. Surface amino groups may then be deprotected with acid or lithium/liquid ammonia. The amino groups serve as a method
商品
Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P4510-1G | 04061834374688 |
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