P4631
Phosphodiesterase I from Bothrops atrox
Type V, crude dried venom, ≥0.01 unit/mg solid
别名:
5′-Exonuclease, Oligonucleate 5′-nucleotidohydrolase
type
Type V
form
crude dried venom
specific activity
≥0.01 unit/mg solid
storage temp.
−20°C
Other Notes
One unit will hydrolyze 1.0 μmole of bis(p-nitrophenyl) phosphate per min at pH 8.8 at 37 °C.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Ronald A Albright et al.
The Journal of biological chemistry, 289(6), 3294-3306 (2013-12-18)
NPP4 is a type I extracellular membrane protein on brain vascular endothelium inducing platelet aggregation via the hydrolysis of Ap3A, whereas NPP1 is a type II extracellular membrane protein principally present on the surface of chondrocytes that regulates tissue mineralization.
José Luis Millán
Calcified tissue international, 93(4), 299-306 (2012-11-28)
Endochondral ossification is a carefully orchestrated process mediated by promoters and inhibitors of mineralization. Phosphatases are implicated, but their identities and functions remain unclear. Mutations in the tissue-nonspecific alkaline phosphatase (TNAP) gene cause hypophosphatasia, a heritable form of rickets and
Nancy Côté et al.
European journal of pharmacology, 689(1-3), 139-146 (2012-06-05)
Calcific aortic valve disease is the most common heart valve disorder. So far, there is no medical treatment for calcific aortic valve disease. The expression of ectonucleotidases, which metabolize nucleotides into phosphate products, may influence the calcification of the aortic
Antonella Marucci et al.
Biochimica et biophysica acta, 1833(6), 1388-1395 (2013-03-19)
Ectonucleotide pyrophosphatase phosphodiesterase 1 (ENPP1) inhibits insulin signaling and action. Understanding the mechanisms underlying ENPP1 expression may help unravel molecular mechanisms of insulin resistance. Recent data suggest a role of ENPP1-3'untraslated region (UTR), in controlling ENPP1 expression. We sought to
Aurora Mejía-Benítez et al.
BMC medical genetics, 14, 21-21 (2013-02-05)
Recent genome wide association studies (GWAS) and previous positional linkage studies have identified more than 50 single nucleotide polymorphisms (SNPs) associated with obesity, mostly in Europeans. We aimed to assess the contribution of some of these SNPs to obesity risk
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