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Merck
CN

P6337

Sigma-Aldrich

Protein Tyrosine Phosphatase Substrate

≥97% (HPLC)

别名:

Insulin Receptor fragment 1142-1153 human, PTPase substrate

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关于此项目

经验公式(希尔记法):
C72H107N19O24
化学文摘社编号:
分子量:
1622.73
MDL编号:
UNSPSC代码:
12352200
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方案

≥97% (HPLC)

储存温度

−20°C

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M J King et al.
FEBS letters, 237(1-2), 137-140 (1988-09-12)
Synthetic peptide 1142-1153 of the insulin receptor was phosphorylated on tyrosine by the insulin receptor and found to be a potent substrate for dephosphorylation by rat liver particulate and soluble phosphotyrosyl protein phosphatases. Apparent Km values were approximately 5 microM.
T O'Hare et al.
The Journal of biological chemistry, 264(1), 602-610 (1989-01-05)
We are interested in developing methods to rigorously characterize the intrinsic enzymatic activity of the insulin receptor. We have previously shown that the intact, kinase active form of the receptor can be separated from inactive forms isolated from human placenta.
L Stadtmauer et al.
The Journal of biological chemistry, 261(21), 10000-10005 (1986-07-25)
Three peptides were synthesized corresponding to potential autophosphorylation sites of the beta subunit of the human insulin receptor. These were peptide 1150 corresponding to amino acids 1142-1153 of the pro-receptor, peptide 960 corresponding to amino acids 952-961 of the proreceptor
Bannwarth, W., and Kitas, E.A.
Helvetica Chimica Acta, 75, 707-707 (1992)

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