P7674
噻嘧啶 (+)-酒石酸盐
别名:
1-Methyl-2-(2-[2-thienyl]ethenyl)-1,4,5,6-tetrahydropyrimidine
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关于此项目
经验公式（希尔记法）:
C11H14N2S · C4H6O6
化学文摘社编号:
分子量:
356.39
UNSPSC Code:
51101500
PubChem Substance ID:
EC Number:
251-501-8
MDL number:
InChI key
VWRCYAZJKNPEQR-NIEARKAZSA-N
InChI
1S/C11H14N2S.C4H6O6/c1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10;5-1(3(7)8)2(6)4(9)10/h2,4-6,9H,3,7-8H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/b6-5+;/t;1-,2-/m.1/s1
SMILES string
O[C@H]([C@@H](O)C(O)=O)C(O)=O.CN1CCCN=C1\C=C\c2cccs2
solubility
H2O: 4.0 mL, clear, colorless to faint yellow or tan (Solvent: 200 mg plus 4.0 mL )
antibiotic activity spectrum
parasites
mode of action
enzyme | inhibits
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Application
Pyrantel is used to study neuronal nicotinic receptors and has been is used to treat parasiticinfections in livestock. Pyrantel tartrate salt is used to study allosteric modulation of the neuronal nicotinic acetylcholine receptors (nAChRs).
Biochem/physiol Actions
Pyrantel is a nematode muscle cell-associated nicotinic agonist for the acetylcholine (ACh) receptor. Cholinesterase inhibitor.
Pyrantel is a nematode muscle cell-associated nicotinic agonist for the acetylcholine (ACh) receptor. This is a cholinesterase inhibitor. It causes spastic muscle paralysis in parasitic worms due to prolonged activation of the excitatory nicotinic acetylcholine (nACh) receptors.
Other Notes
Keep container tightly closed in a dry and well-ventilated place
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
V A Thorpe
Journal of chromatographic science, 26(11), 545-550 (1988-11-01)
Carbadox (CBX), an antibacterial agent, and pyrantel tartrate (PT), an anthelmintic, are formulated either separately or together in swine feeds. The official Association of Official Analytical Chemists (AOAC) spectrophotometric methods for both drugs are long, nonspecific, and require standard addition
[Evaluation of the effectiveness of Banminth in the treatment of ascaridiasis and Capillaria infection in birds].
A Latała et al.
Wiadomosci parazytologiczne, 33(3), 377-382 (1987-01-01)
[Use of small doses of pyrantel tartrate in the treatment of ascaridiasis in laying hens].
A Fagasiński
Wiadomosci parazytologiczne, 33(3), 373-376 (1987-01-01)
E A Kruttlin et al.
Veterinary therapeutics : research in applied veterinary medicine, 2(3), 268-276 (2001-07-01)
Sarcocystis neurona is the etiologic agent of equine protozoal myeloencephalitis, a neurologic disease of horses. The present study was designed to test the hypothesis that pyrantel tartrate can kill S. neurona merozoites growing in equine dermal cell culture. Sarcocystis neurona
[Effect of the treatment of helminth infection with Panacur (Hoechst) and Banminth (Pfizer) on the productivity of laying hens].
A Ramisz
Wiadomosci parazytologiczne, 33(3), 367-372 (1987-01-01)
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