P7674
噻嘧啶 (+)-酒石酸盐
别名:
1-Methyl-2-(2-[2-thienyl]ethenyl)-1,4,5,6-tetrahydropyrimidine
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关于此项目
经验公式（希尔记法）:
C11H14N2S · C4H6O6
化学文摘社编号:
分子量:
356.39
EC 号:
MDL编号:
UNSPSC代码:
51101500
PubChem化学物质编号:
溶解性
H2O: 4.0 mL, clear, colorless to faint yellow or tan (Solvent: 200 mg plus 4.0 mL )
抗生素抗菌谱
parasites
作用机制
enzyme | inhibits
SMILES字符串
O[C@H]([C@@H](O)C(O)=O)C(O)=O.CN1CCCN=C1\C=C\c2cccs2
InChI
1S/C11H14N2S.C4H6O6/c1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10;5-1(3(7)8)2(6)4(9)10/h2,4-6,9H,3,7-8H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/b6-5+;/t;1-,2-/m.1/s1
InChI key
VWRCYAZJKNPEQR-NIEARKAZSA-N
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应用
Pyrantel is used to study neuronal nicotinic receptors and has been is used to treat parasiticinfections in livestock. Pyrantel tartrate salt is used to study allosteric modulation of the neuronal nicotinic acetylcholine receptors (nAChRs).
生化/生理作用
Pyrantel is a nematode muscle cell-associated nicotinic agonist for the acetylcholine (ACh) receptor. Cholinesterase inhibitor.
Pyrantel is a nematode muscle cell-associated nicotinic agonist for the acetylcholine (ACh) receptor. This is a cholinesterase inhibitor. It causes spastic muscle paralysis in parasitic worms due to prolonged activation of the excitatory nicotinic acetylcholine (nACh) receptors.
其他说明
Keep container tightly closed in a dry and well-ventilated place
警示用语：
Danger
危险声明
预防措施声明
危险分类
Acute Tox. 3 Oral
储存分类代码
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
V A Thorpe
Journal of chromatographic science, 26(11), 545-550 (1988-11-01)
Carbadox (CBX), an antibacterial agent, and pyrantel tartrate (PT), an anthelmintic, are formulated either separately or together in swine feeds. The official Association of Official Analytical Chemists (AOAC) spectrophotometric methods for both drugs are long, nonspecific, and require standard addition
[Evaluation of the effectiveness of Banminth in the treatment of ascaridiasis and Capillaria infection in birds].
A Latała et al.
Wiadomosci parazytologiczne, 33(3), 377-382 (1987-01-01)
[Use of small doses of pyrantel tartrate in the treatment of ascaridiasis in laying hens].
A Fagasiński
Wiadomosci parazytologiczne, 33(3), 373-376 (1987-01-01)
E A Kruttlin et al.
Veterinary therapeutics : research in applied veterinary medicine, 2(3), 268-276 (2001-07-01)
Sarcocystis neurona is the etiologic agent of equine protozoal myeloencephalitis, a neurologic disease of horses. The present study was designed to test the hypothesis that pyrantel tartrate can kill S. neurona merozoites growing in equine dermal cell culture. Sarcocystis neurona
R A Valdez et al.
Veterinary parasitology, 60(1-2), 83-102 (1995-11-01)
The bioequivalence of Strongid C and generic pyrantel tartrate was determined in a controlled study using 30 horses with naturally acquired endoparasitic infections. Three horses were randomly allocated to each of ten replicates based on quantitative nematode and ascarid egg
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