P8390
木防己苦毒宁
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关于此项目
经验公式（希尔记法）:
C15H16O6
化学文摘社编号:
分子量:
292.28
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
Form:
powder
form
powder
Quality Segment
SMILES string
[H][C@@]12OC(=O)[C@]([H])([C@@H]1C(C)=C)[C@]3(O)C[C@H]4O[C@]45C(=O)O[C@@]2([H])[C@]35C
InChI
1S/C15H16O6/c1-5(2)7-8-11(16)19-9(7)10-13(3)14(8,18)4-6-15(13,21-6)12(17)20-10/h6-10,18H,1,4H2,2-3H3/t6-,7+,8+,9-,10-,13-,14-,15+/m1/s1
InChI key
PIMZUZSSNYHVCU-KBLUICEQSA-N
General description
Picrotoxinin is a component of picrotoxin and can be derived from plants. It is a non-nitrogenous compound.
Application
Picrotoxinin has been used as an agonist of taste 2 receptor member 14 (TAS2R14) to perform an array-based bitter receptor screening assay and to study the effect of calcium buffering and calcium sensor type on its sensitivity.
Biochem/physiol Actions
Picrotoxinin acts as a potent convulsant.
GABAA 受体拮抗剂；与受体连接的Cl−通道结合。
Features and Benefits
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Glycine Receptor page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Other Notes
Active component of picrotoxin
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Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
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商品
DISCOVER Bioactive Small Molecules for Neuroscience
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P8390-250MG | 04061832092935 |