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Merck
CN

P9732

Sigma-Aldrich

Anti-Potassium Channel Kv3.1b antibody produced in rabbit

affinity isolated antibody, lyophilized powder

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MDL编号:
UNSPSC代码:
12352203
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生物来源

rabbit

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

lyophilized powder

种属反应性

monkey, mouse, rat, canine

技术

immunohistochemistry (frozen sections): suitable
immunoprecipitation (IP): suitable
western blot (chemiluminescent): 1:200

UniProt登记号

储存温度

−20°C

基因信息

rat ... Kcnc1(25327)

免疫原

synthetic peptide corresponding to amino acids 567-585 of rat potassium channel Kv3.1b. This epitope is not present in the alternatively spliced Kv3.1a form.

生化/生理作用

Recognizes full-length Kv3.1b protein.

外形

Lyophilized at ~0.8 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, 5% sucrose and 0.025% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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分析证书(COA)

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J Du et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 16(2), 506-518 (1996-01-15)
The expression of the voltage-gated K(+)-channel subunit Kv3.1b in the developing hippocampus was determined by immunoblot and immunohistochemical techniques. Kv3.1b protein was detected first at postnatal day (P) 8. The Kv3.1b-immunopositive cell number per tissue section reached a maximum at
M Weiser et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 15(6), 4298-4314 (1995-06-01)
Potassium channels play major roles in the regulation of many aspects of neuronal excitability. These channels are particularly well suited for such multiplicity of roles since there is a large diversity of channel types. This diversity contributes to the ability
C J Luneau et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(9), 3932-3936 (1991-05-01)
In an attempt to define the molecular basis of the functional diversity of K+ channels, we have isolated overlapping rat brain cDNAs that encoded a neuronal delayed rectifier K+ channel, K,4, that is structurally related to the Drosophila Shaw protein.
Puja K Parekh et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 43(2), 435-444 (2017-09-01)
Kv3.1 and Kv3.2 voltage-gated potassium channels are expressed on parvalbumin-positive GABAergic interneurons in corticolimbic brain regions and contribute to high-frequency neural firing. The channels are also expressed on GABAergic neurons of the basal ganglia, substantia nigra, and ventral tegmental area
J Rettig et al.
The EMBO journal, 11(7), 2473-2486 (1992-07-01)
Previously, we characterized a Shaker-related family of voltage-gated potassium channels (RCK) in rat brain. Now, we describe a second family of voltage-gated potassium channels in the rat nervous system. This family is related to the Drosophila Shaw gene and has

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