P9799
pGlu-Gly-Arg-Phe amide acetate salt
≥97% (HPLC)
别名:
Antho-RFamide
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关于此项目
经验公式（希尔记法）:
C22H32N8O5
化学文摘社编号:
分子量:
488.54
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
InChI
1S/C22H32N8O5/c23-19(33)16(11-13-5-2-1-3-6-13)30-21(35)14(7-4-10-26-22(24)25)29-18(32)12-27-20(34)15-8-9-17(31)28-15/h1-3,5-6,14-16H,4,7-12H2,(H2,23,33)(H,27,34)(H,28,31)(H,29,32)(H,30,35)(H4,24,25,26)
SMILES string
NC(=N)NCCCC(NC(=O)CNC(=O)C1CCC(=O)N1)C(=O)NC(Cc2ccccc2)C(N)=O
InChI key
CMWHGNOBFVLNTC-UHFFFAOYSA-N
assay
≥97% (HPLC)
UniProt accession no.
application(s)
cell analysis
storage temp.
−20°C
Gene Information
mouse ... Nts(67405)
Biochem/physiol Actions
May be a neurotransmitter at neuromuscular junctions.
Other Notes
Neuropeptide originally isolated from the pennatulid Renilla koellikeri and the sea anemone Anthopleura elegantissima
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
P A Anderson et al.
Cell and tissue research, 267(1), 67-74 (1992-01-01)
The nervous systems of the scyphomedusae Chrysaora hysoscella, Cyanea capillata and Cyanea lamarckii (Phylum Cnidaria) were stained using an anti-serum against the anthozoan neuropeptide Antho-RFamide. Staining was widespread in all three species. In Chrysaora, the antiserum revealed nerve nets in
I D McFarlane et al.
The Journal of experimental biology, 156, 419-431 (1991-03-01)
Antho-RWamide I (less than Glu-Ser-Leu-Arg-Trp-NH2) and Antho-RWamide II (less than Glu-Gly-Leu-Arg-Trp-NH2), the second and third anthozoan neuropeptides to be identified, both induced slow contractions of several endodermal muscles in four species of sea anemone. In a fifth species, Protanthea simplex
D Darmer et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(6), 2555-2559 (1991-03-15)
Neuropeptides containing the carboxylterminal sequence Arg-Phe-NH2 are found throughout the animal kingdom and are important substances mediating neuronal communication. Here, we have cloned the cDNA coding for the precursor protein of the sea anemone neuropeptide (Antho-RFamide) less than Glu-Gly-Arg-Phe-NH2. This
M A Gillis et al.
Journal of neurochemistry, 76(6), 1774-1784 (2001-03-22)
We measured monoamine release from dissociated neurons of the sea pansy Renilla koellikeri, a representative of the most evolutionarily ancient animals with nervous systems, by real-time monitoring of exocytosis using the amperometric method with carbon-fiber microelectrodes. Depolarization-induced, as well as
M Anctil et al.
General pharmacology, 20(3), 381-384 (1989-01-01)
1. Antho-RFamide (pGlu-Gly-Arg-Phe-amide), a neuropeptide recently isolated from the sea pansy Renilla köllikeri induced sustained (tonic) contractions in the rachis and peduncle of the colony, and in the individual autozooid polyps. 2. The threshold concentration for this effect was 5
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