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Merck
CN

PZ0173

Sigma-Aldrich

CP-775146

≥98% (HPLC)

别名:

(S)-2-(3-(1-(2-(4-isopropylphenyl)acetyl)piperidin-3-yl)phenoxy)-2-methylpropanoic acid

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关于此项目

经验公式（希尔记法）:
C26H33NO4
化学文摘社编号:
702680-17-9
分子量:
423.54
MDL编号:
MFCD19690946
UNSPSC代码:
12352200
PubChem化学物质编号:
329823747
NACRES:
NA.77

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质量水平

100

方案

≥98% (HPLC)

表单

powder

旋光性

[α]/D -75 to -83° in methanol

颜色

white to tan

溶解性

DMSO: ≥80 mg/mL

储存温度

−20°C

SMILES字符串

CC(C)C1=CC=C(CC(N2CCC[C@@H](C3=CC(OC(C)(C)C(O)=O)=CC=C3)C2)=O)C=C1

InChI

1S/C26H33NO4.Na/c1-18(2)20-12-10-19(11-13-20)15-24(28)27-14-6-8-22(17-27)21-7-5-9-23(16-21)31-26(3,4)25(29)30;/h5,7,9-13,16,18,22H,6,8,14-15,17H2,1-4H3,(H,29,30);/q;+1/p-1/t22-;/m1./s1

InChI key

YQAGREGJJZRFDN-VZYDHVRKSA-M

生化/生理作用

CP-775146 is a potent and selective PPARα agonist.
Potent and selective PPARα agonist

特点和优势

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Nuclear Receptors (Non-Steroids) and Nuclear Receptors (PPARs) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

象形图

Environment
GHS09

警示用语：

Warning

危险声明

H410

预防措施声明

P273 - P391 - P501

危险分类

Aquatic Acute 1 - Aquatic Chronic 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000059794
0000059793
0000036858
0000035258
061M4723V

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Uxía Nogueira-Recalde et al.
EBioMedicine, 45, 588-605 (2019-07-10)
Ageing-related failure of homeostasis mechanisms contributes to articular cartilage degeneration and osteoarthritis (OA), for which disease-modifying treatments are not available. Our objective was to identify molecules to prevent OA by regulating chondrocyte senescence and autophagy. Human chondrocytes with IL-6 induced

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Nuclear Receptors: PPARs

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