recombinant
expressed in E. coli (histidine-tagged)
assay
≥90% (SDS-PAGE)
form
buffered aqueous solution
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... RNF11(26994)
Biochem/physiol Actions
RNF11 (RING Finger Protein 11) is a RING E3 ubiquitin ligase with potential to mediate ubiquitination and subsequent proteolysis. RNF11 binds numerous proteins in a variety of cellular pathways, including TGFβ and EGFR signaling. RNF11 expression is elevated in breast and prostate cancer. RNF11 may represent an important target for novel cancer therapies.
Physical form
Solution in 50 mM Tris, pH 7.5, 150 mM NaCl, 1 mM DTT, and 30% glycerol (w/v).
存储类别
10 - Combustible liquids
怎么回事?
WGK 1
闪点 (F)
Not applicable
闪点 (°C)
Not applicable
PPE(个人防护设备)
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)