R0635
乙酸视黄酯-水溶性
BioReagent, suitable for cell culture
别名:
维生素 A 醋酸酯, 视黄醇乙酸酯, 维生素 A, 醋酸维生素 A
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关于此项目
经验公式（希尔记法）:
C22H32O2
化学文摘社编号:
分子量:
328.49
NACRES:
NA.75
UNSPSC Code:
12352205
Beilstein/REAXYS Number:
1915439
MDL number:
产品名称
乙酸视黄酯-水溶性, BioReagent, suitable for cell culture
SMILES string
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1
InChI key
QGNJRVVDBSJHIZ-QHLGVNSISA-N
InChI
1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+
biological source
synthetic (organic)
product line
BioReagent
form
powder
technique(s)
cell culture | mammalian: suitable
color
white to light yellow
mp
57-58 °C
solubility
H2O: 400 mg/mL
storage temp.
−20°C
Quality Level
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Application
Retinyl Acetate-Water Soluble has been used as a component of culture medium for secretory cells of venom gland among different Viperidae snakes. It has also been used in testis chunk culturing.
Use to study retinoid regulation of cell transformation; cell differentiation and stem cell development.
Biochem/physiol Actions
Retinyl acetate is known to prevent carcinogenic polycyclic hydrocarbon, methylcholanthrene induced morphological transformation.
General description
Retinyl acetate does not exists naturally, but is derived from retinol. It is considered to be more chemically stable than retinol. For this reason it serves as a dietary supplement for vitamin A source. Vitamin A is found in food of animal origin especially liver and also present in brightly colored vegetables. Vitamin A is a member of carotene family, which is a key component in plant pigments.
Packaging
Package size based on retinol acetate content
Preparation Note
With a minimum of 3 mg retinol acetate per gram; balance methyl-β-cyclodextrin.
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Advanced Nutrition Micronutrie, 23-23 (2018)
Biological Responses in Cancer: Progress toward Potential Applications, 2, 62-62 (2013)
Long-term primary culture of secretory cells of Bothrops jararaca venom gland for venom production in vitro
Yamanouye N, et al.
Nature Protocols, 1(6), 2763-2763 (2006)
Specifications and Criteria for Biochemical Compounds, 1344, 188-188 (1967)
Robert E Chapin et al.
Birth defects research. Part B, Developmental and reproductive toxicology, 107(6), 225-242 (2016-12-27)
The last two decades have seen an increasing search for in vitro models that can replace the use of animals for safety testing. We adapted the methods from a recent nonquantitative report of spermatogenesis occurring in ex vivo mouse testis
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