RAB1092
Human TSG-6 ELISA Kit
for cell culture supernatants, plasma, and serum samples
别名:
Hyaluronate-binding protein, TSG-6, Tumor necrosis factor-inducible gene 6 protein
种属反应性
human
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
输入
sample type cell culture supernatant(s)
sample type serum sample(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.2 ng/ml
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
human ... TNFAIP6(7130)
一般描述
This ELISA antibody pair detects human TSG-6. Other species not yet determined.
应用
Human TSG-6 ELISA Kit has been used to determine galectin G3 and intermediate metabolites level.
生化/生理作用
Tumor necrosis factor (TNF)-α–stimulated gene 6 protein (TSG-6) has been implicated in regulation of cell-cell and cell-matrix interactions during inflammation and tumorigenesis. TSG-6 possess anti-inflammatory properties. It is also known to reduce inflammatory reactions triggered by ischemia in the heart. Thus, it might have a potential role in treating heart disease with other cells such as skeletal myoblasts, fetal myoblasts and embryonic stem cells.
其他说明
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8A - Combustible corrosive hazardous materials
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
S Keisin Wang et al.
The Journal of surgical research, 220, 311-319 (2017-11-29)
The formation of abdominal aortic aneurysms (AAA) is characterized by a dominance of proinflammatory forces that result in smooth muscle cell apoptosis, extracellular matrix degradation, and progressive diameter expansion. Additional defects in the antiinflammatory response may also play a role
Hao Yang et al.
Journal of neuroinflammation, 17(1), 154-154 (2020-05-13)
Neuroinflammation plays a vital role in the development and maintenance of neuropathic pain. Recent evidence has proved that bone marrow mesenchymal stem cells (BMSCs) can inhibit neuropathic pain and possess potent immunomodulatory and immunosuppressive properties via secreting a variety of
Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-?B signaling in resident .
Hosoo , et al.
Blood, 118, 330-338 (2011)
Milad Riazifar et al.
ACS nano, 13(6), 6670-6688 (2019-05-24)
To dissect therapeutic mechanisms of transplanted stem cells and develop exosome-based nanotherapeutics in treating autoimmune and neurodegenerative diseases, we assessed the effect of exosomes secreted from human mesenchymal stem cells (MSCs) in treating multiple sclerosis using an experimental autoimmune encephalomyelitis
Thomas J Bartosh et al.
Cells, 8(9) (2019-09-08)
The use of non-optimal preparations of mesenchymal stem cells (MSCs), such as extensively expanded cells, might be necessary to obtain the large numbers of cells needed for many clinical applications. We previously demonstrated that minimally expanded (early passage) MSCs can
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