应用
硬脂酰辅酶 A 锂盐可用作测定微粒体中硬脂酰辅酶去饱和酶的底物。
辅酶 A 作为酰基载体乙酰辅酶 A 发挥作用。脂酰辅酶 是参与多不饱和脂肪酸合成和PPAR信号通路的饱和脂肪酸代谢产物。硬脂酰辅酶A用于研究硬脂酰辅酶A去饱和酶的特异性和动力学，可导致形成单不饱和脂肪酸。
生化/生理作用
硬脂酰辅酶A是参与多不饱和脂肪酸合成和PPAR信号通路的饱和脂肪酸代谢产物。硬脂酰辅酶A是硬脂酰辅酶A去饱和酶的底物。硬脂酰辅酶A去饱和是不饱和脂肪酸生物合成的关键步骤。辅酶A硬脂酰辅酶A去饱和酶可将硬脂酰辅酶A转化为油酰辅酶A。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Eunha Kim et al.
European journal of pharmacology, 672(1-3), 38-44 (2011-10-06)
Stearoyl-CoA desaturase1 (SCD1) whole body deficiency protects mice from diet-induced obesity. However the specific mechanism of how SCD1 deficiency protects mice from obesity is not clear yet. To understand the tissue-specific role of SCD1 in energy homeostasis, we investigated the
Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity
Ntambi JM, et al.
Proceedings of the National Academy of Sciences of the USA, 99(17), 11482-11486 (2002)
The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1
Miyazaki M, et al.
The Journal of Biological Chemistry, 275(39), 30132-30138 (2000)
M Minville-Walz et al.
Genes & nutrition, 7(2), 209-216 (2011-11-08)
Consumption of trans fatty acids is positively correlated with cardiovascular diseases and with atherogenic risk factors. Trans fatty acids might play their atherogenic effects through lipid metabolism alteration of vascular cells. Accumulation of lipids in vascular smooth muscle cells is
Cancer cell dependence on unsaturated fatty acids implicates stearoyl-CoA desaturase as a target for cancer therapy
Roongta UV, et al.
Molecular Cancer Research, 9(11), 1551-1561 (2011)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持