Anti-phospho-Src (pTyr⁵²⁹) antibody produced in rabbit

Src is a proto-oncogene that regulates neuronal functions, such as nerve cell differentiation. The Src kinase family structurally comprises of SH2, SH3 and kinase domains, as well as a negative regulatory C-terminal tail. Src has also been implicated in functions such as cell growth, development and cell-cell interactions . Anti-phospho-Src (pTyr⁵²⁹) antibody is specific for human, mouse, rat and chicken Src (60 kDa). The product has not been tested for reactivity with Fyn and Yes (92% homologous).

The sequence is conserved in mouse, rat, chicken and frog.

synthetic phosphopeptide derived from the region of Src that contains tyrosine 529 based on the sequence of human src.

Anti-phospho-Src (pTyr⁵²⁹) antibody is suitable for use in western blot (1:1,000 using human platelets or NIH3T3 cells). The product may also be used for immunoprecipitation (1:1000 using HEK293 or HEL cell lysates ) and and immunohistochemistry.

Solution in Dulbecco′s phosphate-buffered saline (without Mg²⁺ and Ca²⁺), pH 7.3, containing 50% glycerol, 1.0 mg/ml BSA (IgG and protease-free) and 0.05% sodium azide.

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