S8251
氯化琥珀胆碱二水合物 二水合物
98.0-102.0%, Cholinergic antagonist, solid
别名:
琥珀酰氯化胆碱
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关于此项目
线性分子式:
[(CH3)3NCH2CH2OCOCH2]2Cl2 · 2H2O
化学文摘社编号:
分子量:
397.34
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-747-4
MDL number:
Beilstein/REAXYS Number:
3922827
产品名称
氯化琥珀胆碱二水合物 二水合物, 98.0-102.0%, solid
InChI key
FFSBEIRFVXGRPR-UHFFFAOYSA-L
InChI
1S/C14H30N2O4.2ClH.2H2O/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;;;/h7-12H2,1-6H3;2*1H;2*1H2/q+2;;;;/p-2
SMILES string
O.O.[Cl-].[Cl-].C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C
assay
98.0-102.0%
form
solid
color
white
solubility
H2O: complete 100 mg/ml, clear to slightly hazy, colorless, H2O: soluble (unstable at pH > 9.)
originator
Novartis
Quality Level
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signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
危险化学品
此项目有
William R Reed et al.
Experimental brain research, 225(2), 205-215 (2012-12-12)
Increasing our knowledge regarding intrafusal fiber distribution and physiology of paraspinal proprioceptors may provide key insights regarding proprioceptive deficits in trunk control associated with low back pain and lead to more effective clinical intervention. The use of vertebral movement as
Franklin Dexter et al.
Anesthesia and analgesia, 116(1), 118-122 (2012-12-12)
Facilities with volatile anesthetic agents stock dantrolene for the treatment of malignant hyperthermia (MH). The availability of dantrolene at these facilities satisfies cost-utility norms even for sites with as few as 1 anesthetic per workday, based on the overall incidence
Walrati Limapichat et al.
The Journal of biological chemistry, 285(12), 8976-8984 (2010-01-14)
The functions of two conserved residues, Phe(135) and Pro(136), located at the apex of the Cys loop of the nicotinic acetylcholine receptor are investigated. Both residues were substituted with natural and unnatural amino acids, focusing on the role of aromaticity
Xinan Xiu et al.
The Journal of biological chemistry, 280(50), 41655-41666 (2005-10-12)
In the Cys loop superfamily of ligand-gated ion channels, a global conformational change, initiated by agonist binding, results in channel opening and the passage of ions across the cell membrane. The detailed mechanism of channel gating is a subject that
Leal G Segura et al.
Paediatric anaesthesia, 23(9), 855-864 (2013-08-08)
Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are associated with life-threatening perioperative complications, including rhabdomyolysis, hyperkalemia, and hyperthermia. Current recommendations contraindicate use of succinylcholine and volatile anesthetics; however, the latter recommendation remains controversial. To review the perioperative outcomes
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