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关于此项目
线性分子式:
[(CH3)3NCH2CH2OCOCH2]2Cl2 · 2H2O
化学文摘社编号:
分子量:
397.34
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-747-4
MDL number:
Beilstein/REAXYS Number:
3922827
产品名称
氯化琥珀胆碱二水合物 二水合物, 98.0-102.0%, solid
Quality Level
assay
98.0-102.0%
form
solid
color
white
solubility
H2O: complete 100 mg/ml, clear to slightly hazy, colorless, H2O: soluble (unstable at pH > 9.)
originator
Novartis
SMILES string
O.O.[Cl-].[Cl-].C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C
InChI
1S/C14H30N2O4.2ClH.2H2O/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;;;/h7-12H2,1-6H3;2*1H;2*1H2/q+2;;;;/p-2
InChI key
FFSBEIRFVXGRPR-UHFFFAOYSA-L
相关类别
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
危险化学品
此项目有
Claus Bretlau et al.
Anesthesia and analgesia, 116(3), 596-601 (2013-02-13)
Succinylcholine is usually metabolized quickly by the butyrylcholinesterase enzyme (BChE) but genetic variants of BChE may prolong the duration of action. The Kalow (K) variant is the most common mutation in the butyrylcholinesterase gene (BCHE), being present in 25% of
Brandon H Cline et al.
BMC neuroscience, 13, 110-110 (2012-09-20)
A number of epidemiological studies have established a link between insulin resistance and the prevalence of depression. The occurrence of depression was found to precede the onset of diabetes and was hypothesized to be associated with inherited inter-related insufficiency of
Leal G Segura et al.
Paediatric anaesthesia, 23(9), 855-864 (2013-08-08)
Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are associated with life-threatening perioperative complications, including rhabdomyolysis, hyperkalemia, and hyperthermia. Current recommendations contraindicate use of succinylcholine and volatile anesthetics; however, the latter recommendation remains controversial. To review the perioperative outcomes
Xinan Xiu et al.
The Journal of biological chemistry, 280(50), 41655-41666 (2005-10-12)
In the Cys loop superfamily of ligand-gated ion channels, a global conformational change, initiated by agonist binding, results in channel opening and the passage of ions across the cell membrane. The detailed mechanism of channel gating is a subject that
Walrati Limapichat et al.
The Journal of biological chemistry, 285(12), 8976-8984 (2010-01-14)
The functions of two conserved residues, Phe(135) and Pro(136), located at the apex of the Cys loop of the nicotinic acetylcholine receptor are investigated. Both residues were substituted with natural and unnatural amino acids, focusing on the role of aromaticity
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| S8251-25G | 04061836960612 |
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