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Merck
CN

S8251

氯化琥珀胆碱二水合物 二水合物

98.0-102.0%, Cholinergic antagonist, solid

别名:

琥珀酰氯化胆碱

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关于此项目

线性分子式:
[(CH3)3NCH2CH2OCOCH2]2Cl2 · 2H2O
化学文摘社编号:
分子量:
397.34
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-747-4
MDL number:
Beilstein/REAXYS Number:
3922827
Assay:
98.0-102.0%
Form:
solid
Quality level:
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产品名称

氯化琥珀胆碱二水合物 二水合物, 98.0-102.0%, solid

InChI key

FFSBEIRFVXGRPR-UHFFFAOYSA-L

InChI

1S/C14H30N2O4.2ClH.2H2O/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;;;/h7-12H2,1-6H3;2*1H;2*1H2/q+2;;;;/p-2

SMILES string

O.O.[Cl-].[Cl-].C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C

assay

98.0-102.0%

form

solid

color

white

solubility

H2O: complete 100 mg/ml, clear to slightly hazy, colorless
H2O: soluble (unstable at pH > 9.)

originator

Novartis

Quality Level

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Application

氯化琥珀胆碱用于研究非洲爪蟾 半胱氨酸环受体的门控机制。4,5

Biochem/physiol Actions

琥珀胆碱是胆碱能拮抗剂和神经肌肉阻断剂。它诱导肌肉膜上乙酰胆碱受体的去极化和肌肉中钾的流出,导致乙酰胆碱受体表达上调的个体发生低钾血症。3
胆碱能拮抗剂,可诱导乙酰胆碱神经元膜的长期去极化;神经肌肉阻断剂。

Features and Benefits

该化合物由 Novartis 开发。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单,请单击此处

Preparation Note

溶液可以在 4℃ 下储存数天。

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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