biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
clone
1SH01, monoclonal
form
buffered aqueous solution
mol wt
protein 50 kDa (SHP1)
species reactivity
human
concentration
~1 mg/mL
technique(s)
immunoprecipitation (IP): 2 μg using 1 mg protein lysate, western blot: 1 μg/mL using HeLa cells
isotype
IgG2b
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... PTPN6(5777)
Immunogen
recombinant human SHP1 protein.
Physical form
Solution in phosphate buffered saline, pH 7.4, containing 0.08% sodium azide.
法规信息
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Prue M Pereira-Fantini et al.
Journal of hepatology, 61(5), 1115-1125 (2014-07-08)
Despite the mortality associated with liver disease observed in patients with short bowel syndrome (SBS), mechanisms underlying the development of SBS-associated liver disease (SBS-ALD) are poorly understood. This study examines the impact of bacterially-mediated bile acid (BA) dysmetabolism on farnesoid
Ivo Buschmann et al.
Journal of molecular medicine (Berlin, Germany), 92(9), 983-994 (2014-05-27)
Arteriogenesis involves the rapid proliferation of preexisting arterioles to fully functional arteries as a compensatory mechanism to overcome circulatory deficits. Stimulation of arteriogenesis has therefore been considered a treatment concept in arterial occlusive disease. Here, we investigated the impact of
M Pesce et al.
Brain, behavior, and immunity, 41, 251-260 (2014-05-06)
Recent lines of research have boosted awareness of the immunological facets of schizophrenia. However, associations with protein tyrosine phosphatase regulators have never been reported. The aim of our study was to investigate the expression and promoter status methylation of phosphatase
Charlotte Viant et al.
Nature communications, 5, 5108-5108 (2014-10-31)
Natural killer (NK) cells are cytotoxic innate lymphoid cells that are involved in immune defense. NK cell reactivity is controlled in part by MHC class I recognition by inhibitory receptors, but the underlying molecular mechanisms remain undefined. Using a mouse
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