硫前列酮

Name: 硫前列酮
Brand: SIGMA

≥95% (HPLC), oil

别名:

(5Z,11α,13E,15R)--11,15-Dihydroxy-9-oxo-16-phenoxy-17,18,19,20-tetranorprosta-5,13-dienoic acid methane sulfonamide, CP-34089, SHB-286, ZK-57671

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所有图片(1)

About This Item

经验公式（希尔记法）:

C₂₃H₃₁NO₇S

CAS Number:

60325-46-4

分子量:

465.56

EC 号:

262-173-0

MDL编号:

MFCD00216056

UNSPSC代码:

12352200

PubChem化学物质编号:

24724621

NACRES:

NA.77

质量水平

100

方案

≥95% (HPLC)

表单

oil

颜色

colorless to yellow-brown

溶解性

DMSO: >10 mg/mL

运输

wet ice

储存温度

−20°C

SMILES字符串

CS(=O)(=O)NC(=O)CCC\C=C/C[C@@H]1[C@@H](\C=C\[C@@H](O)COc2ccccc2)[C@H](O)CC1=O

InChI

1S/C23H31NO7S/c1-32(29,30)24-23(28)12-8-3-2-7-11-19-20(22(27)15-21(19)26)14-13-17(25)16-31-18-9-5-4-6-10-18/h2,4-7,9-10,13-14,17,19-20,22,25,27H,3,8,11-12,15-16H2,1H3,(H,24,28)/b7-2-,14-13+/t17-,19-,20-,22-/m1/s1

InChI key

UQZVCDCIMBLVNR-TWYODKAFSA-N

应用

Human chondrocytes³ and mouse adrenal chromaffin cells⁴ were treated with sulprostone to study the biological effects of PGE₂.

生化/生理作用

Selective EP₃ prostanoid receptor agonist.

Sulprostone is an analog of prostaglandin E₂ (PGE₂)¹and antagonizes vasopressin-induced antidiuretic responses in cells from rat renal inner medullae by a mechanism that involves activation of Rho.²