SAB1300783
Anti-CLC4 (C-term) antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
别名:
Anti-CLCN4, Anti-Chloride channel protein 4, Anti-ClC-4
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IF, WB
Citations:
3
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
indirect ELISA: 1:1000, indirect immunofluorescence: 1:10-1:50, western blot: 1:100-1:500
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CLC4(1183)
General description
CLCN4 (chloride channel 4) gene codes for the chloride/hydrogen ion exchanger CIC-4. It is abundantly expressed in brain. ClC-4 belongs to the ClC transporter branch. It is present in the intracellular membranes of the brain, muscle and liver. This gene is located on human chromosome Xp22.3.
Immunogen
CLC4 (NP_001821, 662-699)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CLC4.
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CLC4.
Biochem/physiol Actions
CLCN4 (chloride channel 4) is associated with X-linked intellectual disability and epilepsy. ClC-4 helps to interchange anion/proton with variable stoichiometry.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
De novo and inherited mutations in the X-linked gene CLCN4 are associated with syndromic intellectual disability and behavior and seizure disorders in males and females.
Palmer EE, et al.
Molecular Psychiatry, 23(2), 222?230-222?230 (2016)
Channel-like slippage modes in the human anion/proton exchanger ClC-4.
Alekov AK and Fahlke C
The Journal of General Physiology, 133(5), 485-496 (2009)
Application of microarrays to the analysis of the inactivation status of human X-linked genes expressed in lymphocytes.
Craig IW, et al.
European Journal of Human Genetics, 12(8), 639-639 (2004)
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