免疫原
Antibody was raised against a 17 amino acid peptide near the carboxy terminus of human ARR3.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Supplied at 1 mg/mL in PBS with 0.02% sodim azide.
其他说明
The action of this antibody can be blocked using blocking peptide SBP3501086.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
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Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Vsevolod V Gurevich et al.
Pharmacology & therapeutics, 110(3), 465-502 (2006-02-08)
The 4 mammalian arrestins serve as almost universal regulators of the largest known family of signaling proteins, G-protein-coupled receptors (GPCRs). Arrestins terminate receptor interactions with G proteins, redirect the signaling to a variety of alternative pathways, and orchestrate receptor internalization
Xiufeng Song et al.
The Journal of biological chemistry, 284(1), 685-695 (2008-11-13)
Arrestins bind active phosphorylated G protein-coupled receptors, precluding G protein activation and channeling signaling to alternative pathways. Arrestins also function as mitogen-activated protein kinase (MAPK) scaffolds, bringing together three components of MAPK signaling modules. Here we have demonstrated that all
Jungwon Seo et al.
The Journal of biological chemistry, 286(32), 27894-27901 (2011-07-01)
Arrestins bind active phosphorylated G protein-coupled receptors, blocking G protein activation and channeling the signaling to G protein-independent pathways. Free arrestin-3 and receptor-bound arrestin-3 scaffold the ASK1-MKK4-JNK3 module, promoting JNK3 phosphorylation, whereas highly homologous arrestin-2 does not. Here, we used
A Murakami et al.
FEBS letters, 334(2), 203-209 (1993-11-15)
We have been using a differential cDNA cloning approach to isolate human retina-specific and retina-enriched genes [1]. A 1,314 bp cDNA was isolated by this approach, representing a highly retina-specific message encoding a 388 amino acid protein showing 58%, 50%
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