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Merck
CN

SAB3501086

Anti-ARR3 antibody produced in rabbit

affinity isolated antibody

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 43 kDa

species reactivity

human, rat, mouse

concentration

1 mg/mL

technique(s)

ELISA: suitable, immunoblotting: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... ARR3(407)

Immunogen

Antibody was raised against a 17 amino acid peptide near the carboxy terminus of human ARR3.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 1 mg/mL in PBS with 0.02% sodim azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3501086.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Jungwon Seo et al.
The Journal of biological chemistry, 286(32), 27894-27901 (2011-07-01)
Arrestins bind active phosphorylated G protein-coupled receptors, blocking G protein activation and channeling the signaling to G protein-independent pathways. Free arrestin-3 and receptor-bound arrestin-3 scaffold the ASK1-MKK4-JNK3 module, promoting JNK3 phosphorylation, whereas highly homologous arrestin-2 does not. Here, we used
Vsevolod V Gurevich et al.
Pharmacology & therapeutics, 110(3), 465-502 (2006-02-08)
The 4 mammalian arrestins serve as almost universal regulators of the largest known family of signaling proteins, G-protein-coupled receptors (GPCRs). Arrestins terminate receptor interactions with G proteins, redirect the signaling to a variety of alternative pathways, and orchestrate receptor internalization
A Murakami et al.
FEBS letters, 334(2), 203-209 (1993-11-15)
We have been using a differential cDNA cloning approach to isolate human retina-specific and retina-enriched genes [1]. A 1,314 bp cDNA was isolated by this approach, representing a highly retina-specific message encoding a 388 amino acid protein showing 58%, 50%



全球贸易项目编号

货号GTIN
SBP3501086-0.05MG04061832175362