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Merck
CN

SBR00097

Sigma-Aldrich

Sancycline

≥95% (H-NMR), powder

别名:

6-Demethyl-6-deoxytetracycline, Bonomycin, Norcycline

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关于此项目

经验公式(希尔记法):
C21H22N2O7
CAS Number:
分子量:
414.41
UNSPSC代码:
51101500
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质量水平

方案

≥95% (H-NMR)

表单

powder

颜色

yellow to brown

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria
mycoplasma

作用机制

protein synthesis | inhibits

运输

ambient

储存温度

−20°C

SMILES字符串

CN(C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C(=CC=C4)O)C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O

InChI

1S/C21H22N2O7/c1-23(2)15-10-7-9-6-8-4-3-5-11(24)12(8)16(25)13(9)18(27)21(10,30)19(28)14(17(15)26)20(22)29/h3-5,9-10,15,24-25,28,30H,6-7H2,1-2H3,(H2,22,29)/t9-,10-,15-,21-/m0/s1

InChI key

MTCQOMXDZUULRV-ADOAZJKMSA-N

一般描述

Sancycline is an antibioitic which belongs to the class of compounds known as tetracycline antibiotics. It is a semisynthetic derivative of naturally occurring tetracycline and is used in the treatment of bacterial infections caused by susceptible organisms. Sancycline is active against a wide range of Gram-positive and Gram-negative bacteria, as well as atypical bacteria such as Mycoplasma and Chlamydia species.

生化/生理作用

Sancycline inhibits bacterial protein synthesis by binding to the 30S subunit of the bacterial ribosome. Specifically, it binds to the A site of the ribosome and blocks the attachment of aminoacyl-tRNA molecules to the ribosome, which is necessary for the addition of new amino acids to the growing polypeptide chain. This ultimately leads to the inhibition of bacterial protein synthesis and bacterial death.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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