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Merck
CN

SCP0173

Sigma-Aldrich

KISS-1 125-144

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关于此项目

经验公式(希尔记法):
C80H122N32O27
分子量:
1964.02
UNSPSC代码:
12352200
NACRES:
NA.32
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方案

≥95% (HPLC)

表单

lyophilized

组成

Peptide Content, ≥75%

储存条件

protect from light

储存温度

−20°C

Amino Acid Sequence

Glu-Ala-Ala-Pro-Gly-Asn-His-Gly-Arg-Ser-Ala-Gly-Arg-Gly-Trp-Gly-Ala-Gly-Ala-Gly-Gln

应用

Kisspeptins are a family of peptides encoded by the KISS-1 gene that are involved in GPR54 mediated cell signaling. Kiss-1 gene products are involved in metastasis suppression and the regulation of gonadotropin-releasing hormone (GnRH) secretion. A variety of kisspeptin peptides are available for use to study their unique functions.

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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E Papaoiconomou et al.
In vivo (Athens, Greece), 25(3), 343-354 (2011-05-18)
The Kiss-1 gene encodes a secreted protein that is proteolytically cleaved to produce a number of structurally related peptides, with high interspecies conservation, globally termed kisspeptins. The original niche for the role of kisspeptin in human physiology is derived from
Jenny Clarkson et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 28(35), 8691-8697 (2008-08-30)
Kisspeptin and its receptor GPR54 have recently been identified as key signaling partners in the neural control of fertility in animal models and humans. The gonadotropin-releasing hormone (GnRH) neurons represent the final output neurons of the neural network controlling fertility
Naresh Kumar Hanchate et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(3), 932-945 (2012-01-21)
Reproduction is controlled in the brain by a neural network that drives the secretion of gonadotropin-releasing hormone (GnRH). Various permissive homeostatic signals must be integrated to achieve ovulation in mammals. However, the neural events controlling the timely activation of GnRH
Rafael Pineda et al.
Progress in brain research, 181, 55-77 (2010-05-19)
Reproductive maturation and function are maintained by a complex neurohormonal network that integrates at the so-called hypothalamic-pituitary-gonadal (HPG) axis. This system is hierarchically controlled by the decapeptide, GnRH, which in turn is under the dynamic regulation of multiple stimulatory and

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