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Merck
CN

SMB00292

Sigma-Aldrich

Fengycin

≥90%

别名:

Fengycin, Plipastatin

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关于此项目

经验公式(希尔记法):
C72H110N12O20
分子量:
1463.71
UNSPSC代码:
51102829
NACRES:
NA.85
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生物来源

Bacillus subtilis

质量水平

方案

≥90%

表单

powder

颜色

, Off-White to Light Yellow to Light Brown

抗生素抗菌谱

fungi

作用机制

cell membrane | interferes

储存温度

2-8°C

一般描述

Chemical structure: peptide
Fengycin is a lipopeptide complex which is synthesized by Bacillus subtilis strain F-29-3. It is an antifungal compound, and is made up of two components namely, fengycin A and fengycin B. Fengycin A contains 1 D-Ala, 1 L-Ile, 1 L-Pro, 1 D-allo-Thr, 3 L-Glx, 1 D-Tyr, 1 L-Tyr, 1 D-Orn, whereas fengycin B contains D-Val instead of D-Ala.

应用

Fengycin may be used for the sterilization of E. coli., and for the inactivation of spores of Bacillus cereus.

生化/生理作用

Fengycin shows antifungal properties against filamentous fungi, but has no action against yeast and bacteria. Certain unsaturated fatty acids facilitate the antifungal property, whereas sterols, phospholipids and oleic acid act as antagonists. It produces morphological abnormalities in fungi including curling, bulging and empyting of hyphae. Thus, it mainly functions through its effects on the plasma membrane.

包装

5MG

制备说明

Store at 2 to 8 °C. (Keep container tightly closed in a dry and well-ventilated place. Light sensitive.)

其他说明

Keep container tightly closed in a dry and well-ventilated place. Light sensitive.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Plipastatins: new inhibitors of phospholipase A2, produced by Bacillus cereus BMG302-fF67
Nishikiori, T., et al
The Journal of Antibiotics, 39, 745-745 (1986)
Optimization of inactivation of endospores of Bacillus cereus in milk by surfactin and fengycin using a response surface method.
Huang X
International Journal of Peptide Research and Therapeutics, 14(2), 89-95 (2008)
N Vanittanakom et al.
The Journal of antibiotics, 39(7), 888-901 (1986-07-01)
Fengycin is an antifungal lipopeptide complex produced by Bacillus subtilis strain F-29-3. It inhibits filamentous fungi but is ineffective against yeast and bacteria. The inhibition is antagonized by sterols, phospholipids and oleic acid, whereas two other unsaturated fatty acids increase
Optimization of sterilization of Escherichia coli in milk by surfactin and fengycin using a response surface method.
Huang X
Current Microbiology, 56(4), 376-381 (2008)
Marc Ongena et al.
Environmental microbiology, 9(4), 1084-1090 (2007-03-16)
Multiple strains of Bacillus spp. were demonstrated to stimulate plant defence responses. However, very little is known about the nature of molecular determinants secreted by these Gram-positive bacteria that are responsible for the elicitation of the induced systemic resistance (ISR)

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