SMB00354
梣酮
≥98% (HPLC)
别名:
3-(3-Furyl)-3a,4,5,6-tetrahydro-3a,7-dimethylphthalide
方案
≥98% (HPLC)
表单
powder
应用
metabolomics
vitamins, nutraceuticals, and natural products
储存温度
−20°C
SMILES字符串
CC1=C(C(O[C@H]2C3=COC=C3)=O)[C@@]2(C)CCC1
InChI
1S/C14H16O3/c1-9-4-3-6-14(2)11(9)13(15)17-12(14)10-5-7-16-8-10/h5,7-8,12H,3-4,6H2,1-2H3/t12-,14+/m0/s1
InChI key
XYYAFLHHHZVPRN-GXTWGEPZSA-N
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一般描述
Fraxinellone is a terpenoid found in the root bark of Dictamnus albus. It belongs to a small group of degraded limonoids.
生化/生理作用
Fraxinellone possesses neuroprotective and vasorelaxing activities as well as anti-inflammatory properties. Fraxinellone has been used as a potent therapeutic for T-cell-mediated liver disorders in humans.
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral - Repr. 2
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Selective triggering of apoptosis of concanavalin A-activated T cells by fraxinellone for the treatment of T-cell-dependent hepatitis in mice
Sun Y, et al.
Biochemical Pharmacology, 77(11), 1717-1724 (2009)
Fraxinellone inhibits lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 expression by negatively regulating nuclear factor-kappa B in RAW 264.7 macrophages cells.
Kim J H, et al.
Biological & Pharmaceutical Bulletin, 32(6), 1062-1068 (2009)
Antimutagenic Activity of Isofraxinellone from Dictamnus dasycarpus
Miyazawa M, et al.
Journal of Agricultural and Food Chemistry, 43(6), 1428-1431 (1995)
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