SMB01046
Phomopsolide B
≥90% (LC/MS-ELSD)
别名:
(+)-Phomopsolide B, 2-Butenoic acid, 2-methyl-, (2S,3S)-2-[(1E,3S,4S)-3,4-dihydroxy-1-pentenyl]-3,6-dihydro-6-oxo-2H-pyran-3-yl ester, (2E)- (9CI)
生物来源
plant
方案
≥90% (LC/MS-ELSD)
表单
solid
分子量
296.32
溶解性
water: soluble
应用
metabolomics
vitamins, nutraceuticals, and natural products
储存温度
−20°C
SMILES字符串
O1[C@H]([C@H](C=CC1=O)OC(=O)\C(=C\C)\C)\C=C\[C@H](O)[C@@H](O)C
InChI
1S/C15H20O6/c1-4-9(2)15(19)21-13-7-8-14(18)20-12(13)6-5-11(17)10(3)16/h4-8,10-13,16-17H,1-3H3/b6-5+,9-4+/t10-,11-,12-,13-/m0/s1
InChI key
JTHHOHSDOJJNFN-HIWLEQICSA-N
一般描述
Phomopsolide B is a phytotoxin, a natural bioactive compound commonly derived from Penicillium sp. but also reported in Diaporthe phaseolorum and Phomopsis sp. fungi. It has demonstrated the ability to induce apoptosis in cancer cells, inhibit the growth of bacteria and fungi, and modulate immune responses. This secondary metabolite exhibits various biological activities, including antifungal, antibacterial, and anticancer properties.
应用
It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.
特点和优势
- High quality compound suitable for multiple research applications
- Compatible with HPLC and mass spectrometry techniques
其他说明
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储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
D B Stierle et al.
Journal of natural products, 60(11), 1207-1209 (1997-12-11)
Investigation of the bioactive compounds from a Penicillium sp. isolated from the inner bark of the Pacific yew, Taxus brevifolia, led to the isolation of the known furanone 1, and a series of phomopsolides. The phomopsolide fractions contained phomopsolides A
Andrea A Stierle et al.
Natural product communications, 9(1), 87-90 (2014-03-26)
For the past fifteen years we have studied the secondary metabolites of extremophilic fungi from the Berkeley Pit, an abandoned acid mine waste lake. Fungi associated with an acid-tolerant alga have also been harvested from the Pit. Penicillium clavigerum Demelius
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