SML0258
CPPG
≥98% (HPLC)
别名:
(R,S)-α-Cyclopropyl-4-phosphonophenylglycine
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关于此项目
经验公式（希尔记法）:
C11H14NO5P
化学文摘社编号:
分子量:
271.21
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
方案
≥98% (HPLC)
表单
powder
储存条件
desiccated
颜色
white to beige
溶解性
H2O: >5 mg/mL
储存温度
room temp
SMILES字符串
NC(C1CC1)(C(O)=O)c2ccc(cc2)P(O)(O)=O
InChI
1S/C11H14NO5P/c12-11(10(13)14,7-1-2-7)8-3-5-9(6-4-8)18(15,16)17/h3-7H,1-2,12H2,(H,13,14)(H2,15,16,17)
InChI key
IGODGTDUQSMDQU-UHFFFAOYSA-N
生化/生理作用
(R,S)-α-Cyclopropyl-4-phosphonophenylglycine (CPPG) can be used in combination with scopolamine to treat the depressive disorder.
CPPG is a potent group II/III metabotropic glutamate receptor antagonist, with approximately 20-fold selectivity for mGlu group III over group II (IC50 values of 2.2 and 46.2 nM respectively).
CPPG is a potent group II/III metabotropic glutamate receptor antagonist.
特点和优势
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