SML0351
CPDT
≥96% (HPLC)
别名:
5,6-Dihydro-Cyclopenta[c]-1,2-dithiole-3(4H)-thione, CJ 11788, SNU2A
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关于此项目
经验公式（希尔记法）:
C6H6S3
化学文摘社编号:
分子量:
174.31
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
产品名称
CPDT, ≥96% (HPLC)
InChI
1S/C6H6S3/c7-6-4-2-1-3-5(4)8-9-6/h1-3H2
SMILES string
S=C1SSC2=C1CCC2
InChI key
AVSGTGUIBQOXJK-UHFFFAOYSA-N
assay
≥96% (HPLC)
form
powder
color
faintly red to very dark red
solubility
DMSO: 2 mg/mL (warmed)
storage temp.
2-8°C
Quality Level
Application
5,6-dihydrocyclopenta-1,2-dithiole-3-thione (CPDT) has been used to study its protective effects and the underlying mechanism in diabetic cardiomyopathy.
Biochem/physiol Actions
5,6-dihydrocyclopenta-1,2-dithiole-3-thione (CPDT) is a phase II enzyme inducer. It exhibits protective actions against chemical carcinogens.
CPTD (SNU2A) is a cytoprotective agent that protects mitochondria during cell stress by increasing antioxidant capacity. CPTD inhibits phosphorylation and activation of Fyn, which maintains AMPK activity and activation of Nrf2.
CPTD is an anti-oxidant, cytoprotective agent.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Chronic 3
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Ying Miao et al.
BioMed research international, 2017, 9167450-9167450 (2018-02-07)
Diabetic cardiomyopathy (DCM) is a common heart disease. The Phase II enzyme inducer (CPDT) is a complex enzyme that promotes the expression of antioxidant enzymes through activating nuclear factor erythroid 2-related factor 2 (Nrf2); these compounds have been shown to
Wenyan Guo et al.
International journal of biological macromolecules, 135, 619-629 (2019-05-28)
The aim of this study was to investigate the effects of biomacromolecules mannan/β-glucans from yeast cell wall (BYCW) to alleviate Deoxynivalenol(DON)-induced injury. Considering that DON has strong oxidizing effect and stimulates autophagy and apoptosis, we examined the effects of BYCW
Matías Regiart et al.
Analytica chimica acta, 963, 83-92 (2017-03-25)
We report a hybrid glass-poly (dimethylsiloxane) microfluidic immunosensor for epidermal growth factor receptor (EGFR) determination, based on the covalent immobilization of anti-EGFR antibody (anti-EGFR) on amino-functionalized mesoporous silica (AMS) retained in the central channel of a microfluidic device. The synthetized
So Jung Park et al.
ACS applied materials & interfaces, 12(43), 49165-49173 (2020-09-30)
Control of the cross-linking reaction is imperative when developing a sophisticated in situ forming hydrogel in the body. In this study, a heteroarmed thermoresponsive (TR) nanoparticle was designed to investigate the mechanism of controlling reactivity of the functional groups introduced
Hsiu-Pen Lin et al.
Macromolecular bioscience, 20(6), e2000049-e2000049 (2020-04-08)
Cationic polymers exhibit high cytotoxicity via strong interaction with cell membranes. To reduce cell membrane damage, a hydrophilic polymer is introduced to the cationic nanoparticle surface. The hydrophilic polymer coating of cationic nanoparticles resulted in a nearly neutral nanoparticle. These
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