BAY-X-1005

Name: BAY-X-1005
Brand: SIGMA

≥98% (HPLC)

别名:

α-Cyclopentyl-4-(2-quinolinylmethoxy)-(R)-benzeneacetic acid, (αR)-α-Cyclopentyl-4-(2-quinolinylmethoxy)-benzeneacetic acid, DG 031, Velifapon, Veliflapon

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所有图片(1)

About This Item

经验公式（希尔记法）:

C₂₃H₂₃NO₃

CAS Number:

128253-31-6

分子量:

361.43

MDL编号:

MFCD00870329

UNSPSC代码:

12352200

PubChem化学物质编号:

329825406

NACRES:

NA.77

质量水平

100

方案

≥98% (HPLC)

表单

powder

颜色

white to beige

溶解性

DMSO: 5 mg/mL (clear solution)

储存温度

2-8°C

SMILES字符串

OC(=O)[C@H](C1CCCC1)c2ccc(OCc3ccc4ccccc4n3)cc2

InChI

1S/C23H23NO3/c25-23(26)22(17-6-1-2-7-17)18-10-13-20(14-11-18)27-15-19-12-9-16-5-3-4-8-21(16)24-19/h3-5,8-14,17,22H,1-2,6-7,15H2,(H,25,26)/t22-/m1/s1

InChI key

ZEYYDOLCHFETHQ-JOCHJYFZSA-N

生化/生理作用

Bay-X-1005 is a potent inhibitor of 5-lipoxygenase activating protein (FLAP).

Bay-X-1005 is a potent inhibitor of 5-lipoxygenase activating protein (FLAP). Bay-X-1005 inhibits A23187-induced LTB4 production in human leucocytes with an IC₅₀ value of 220 nM, and blocks IgE mediated airway contractions.