SML0482
3CAI
≥95% (HPLC)
别名:
2-Chloro-1-(1H-indol-3-yl)ethanone, 3-Chloroacetyl-indole, Chloromethyl indol-3-yl ketone
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C10H8ClNO
化学文摘社编号:
分子量:
193.63
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
产品名称
3CAI, ≥95% (HPLC)
InChI
1S/C10H8ClNO/c11-5-10(13)8-6-12-9-4-2-1-3-7(8)9/h1-4,6,12H,5H2
SMILES string
O=C(CCl)C1=CNC2=C1C=CC=C2
InChI key
LLZQFAXTCYDVTR-UHFFFAOYSA-N
assay
≥95% (HPLC)
form
powder
storage condition
desiccated
protect from light
color
yellow to brown
solubility
DMSO: 5 mg/mL, clear
shipped in
wet ice
storage temp.
−20°C
Biochem/physiol Actions
3CAI is a potent and specific allosteric inhibitor of Akt1 and Akt2.
3CAI is an orally active, potent and specific allosteric inhibitor of Akt1 and Akt2 that directly binds to Ak1 and Akt2 in an ATP noncompetitive manner.
Features and Benefits
This compound is featured on the PKB/Akt page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
新产品
此项目有
Ji-Eun Kim et al.
Cell death & disease, 9(5), 546-546 (2018-05-12)
Recently, we have reported that heat shock protein B1 (HSPB1) and purinergic receptor P2X7 (P2RX7) are involved in astroglial autophagy (clasmatodendrosis), following status epilepticus (SE). However, the underlying mechanisms of astroglial autophagy have not been completely established. In the present
[Photometric determination of 3-chloroacetyl indole in the air].
E I Kosterina et al.
Gigiena i sanitariia, (2)(2), 48-49 (1988-02-01)
商品
We offer many products related to PKB/Akt for your research needs.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持