SML0482
3CAI
≥95% (HPLC)
别名:
2-Chloro-1-(1H-indol-3-yl)ethanone, 3-Chloroacetyl-indole, Chloromethyl indol-3-yl ketone
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关于此项目
经验公式（希尔记法）:
C10H8ClNO
化学文摘社编号:
分子量:
193.63
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
方案
≥95% (HPLC)
表单
powder
储存条件
desiccated
protect from light
颜色
yellow to brown
溶解性
DMSO: 5 mg/mL, clear
运输
wet ice
储存温度
−20°C
SMILES字符串
O=C(CCl)C1=CNC2=C1C=CC=C2
InChI
1S/C10H8ClNO/c11-5-10(13)8-6-12-9-4-2-1-3-7(8)9/h1-4,6,12H,5H2
InChI key
LLZQFAXTCYDVTR-UHFFFAOYSA-N
生化/生理作用
3CAI is a potent and specific allosteric inhibitor of Akt1 and Akt2.
3CAI is an orally active, potent and specific allosteric inhibitor of Akt1 and Akt2 that directly binds to Ak1 and Akt2 in an ATP noncompetitive manner.
特点和优势
This compound is featured on the PKB/Akt page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
法规信息
新产品
此项目有
Ji-Eun Kim et al.
Cell death & disease, 9(5), 546-546 (2018-05-12)
Recently, we have reported that heat shock protein B1 (HSPB1) and purinergic receptor P2X7 (P2RX7) are involved in astroglial autophagy (clasmatodendrosis), following status epilepticus (SE). However, the underlying mechanisms of astroglial autophagy have not been completely established. In the present
[Photometric determination of 3-chloroacetyl indole in the air].
E I Kosterina et al.
Gigiena i sanitariia, (2)(2), 48-49 (1988-02-01)
实验方案
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