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Merck
CN

SML1566

Sigma-Aldrich

Leucinostatin A+B mixture

≥95% (mixture of Leucinostatin A+B, HPLC), (Paecilomyces lilacinus)

别名:

Antibiotic 1907-II, Antibiotic 1907-VIII, Leucinostatin A+B

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关于此项目

UNSPSC代码:
51111800
NACRES:
NA.77
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质量水平

生物来源

(Paecilomyces lilacinus)

方案

≥95% (mixture of Leucinostatin A+B, HPLC)

表单

powder

溶解性

DMF: 10 mg/mL
DMSO: 10 mg/mL
ethanol: 10 mg/mL
methanol: 10 mg/mL

储存温度

−20°C

生化/生理作用

Leucinostatins A and B are the major components of an atypical nonapeptide complex produced by Paecilomyces lilacinus.
Leucinostatins A and B are the major components of an atypical nonapeptide complex produced by Paecilomyces lilacinus. Leucinostatins display broad bio-activity against gram-positive bacteria, fungi, plants and tumor cell lines. They play a role as uncouplers in the inner mitochondria membrane and inhibit mitochondrial ATP synthesis. Recently, interest in Leucinostatins has focused on other aspects such as understanding their activity: insulin-like growth factor I regulators, ionophore, inhibitors of cell surface expression of viral glycoproteins and their potent in vitro and in vivo anti-trypanosomal activity.

制备说明

Mixture of Leucinostatin A (Cas# 76600-38-9 / MF: C62H111N11O13) and Leucinostatin B (Cas# 76663-52-0 / MF: C61H109N11O13).

其他说明

Mixture of Leucinostatin A (Cas# 76600-38-9 / MF: C62H111N11O13) and Leucinostatin B (Cas# 76663-52-0 / MF: C61H109N11O13).
Stable at −20 °C for at least 2 years.

分析物

说明

    Leuconostatin A
    Leucinostatin B

储存分类代码

11 - Combustible Solids

WGK

WGK 3

法规信息

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Qingkang Lyu et al.
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Dysregulation of retinal pigment epithelium (RPE) cells is the main cause of a variety of ocular diseases. Potentially heat shock proteins, by preventing molecular and cellular damage and modulating inflammatory disease, may exert a protective role in eye disease. In

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