SML2547
KCC-07
≥98% (HPLC)
别名:
3-[[4-(2-Pyridinyl)-2-thiazolyl]amino]phenol
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关于此项目
经验公式（希尔记法）:
C14H11N3OS
化学文摘社编号:
分子量:
269.32
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC1=CC(NC2=NC(C3=NC=CC=C3)=CS2)=CC=C1
InChI key
GIGNWEDIMLUWCT-UHFFFAOYSA-N
Biochem/physiol Actions
KCC-07 is a brain penetrant, potent and selective inhibitor of MBD2 (methyl-CpG-binding domain protein 2) that inhibits binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling. KCC-07 inhibits medulloblastoma cell proliferation, and inhibits tumor growth in mice xenograft models of medulloblastoma.
brain penetrant, potent and selective inhibitor of MBD2 that inducing anti-proliferative BAI1/p53/p21 signaling
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable