SML2675
CuET
≥97% (HPLC)
别名:
Copper bis(N,N-diethyldithiocarbamate), Cupric diethyldithiocarbamate, Merkupral, NSC 177697, bis(N,N-Diethyldithiocarbamato)copper(II)
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关于此项目
经验公式（希尔记法）:
C10H20CuN2S4
化学文摘社编号:
分子量:
360.09
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥97% (HPLC)
Form:
powder
Storage condition:
desiccated
assay
≥97% (HPLC)
form
powder
storage condition
desiccated
color
dark green to black
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
CCN(CC)C(S[Cu]SC(N(CC)CC)=S)=S
InChI
1S/2C5H11NS2.Cu/c2*1-3-6(4-2)5(7)8;/h2*3-4H2,1-2H3,(H,7,8);/q;;+2/p-2
InChI key
OBBCYCYCTJQCCK-UHFFFAOYSA-L
Biochem/physiol Actions
CuET, a metabolite of disulfiram, is an inhibitor of p97 segregase adaptor NPL4 that exhibits potent anti-cancer effects. Apparently CuET binds NPL4 and induces its aggregation, which disables the vital p97–NPL4–UFD1 pathway and induces to cell death.
Inhibitor of NPL4
存储类别
11 - Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable