SML2885
Ac-SDKP trifluoroacetate
≥95% (HPLC)
别名:
Ac-SDKP-OH trifluoroacetate, Ac-Ser-Asp-Lys-Pro-OH trifluoroacetate, AcSDKP trifluoroacetate, Goralatide trifluoroacetate, N-acetyl-L-seryl-L-a-aspartyl-L-lysyl-L-proline trifluoroacetate, N-acetyl-Ser-Asp-Lys-Pro-OH trifluoroacetate, Thymosin ß4 (1-4) trifluoroacetate, Tß4 (1-4) trifluoroacetate
登录查看公司和协议定价
所有图片(1)
About This Item
经验公式（希尔记法）:
C20H33N5O9 · xC2HF3O2
CAS Number:
分子量:
487.50 (free base basis)
UNSPSC代码:
12352200
NACRES:
NA.77
生化/生理作用
Originally characterized as a "spleen colony-forming units (CFU-S) inhibitor" for its activity against hematopoietic pluripotent stem cell proliferation, Ac-SDKP (Goralatide) is an immunomodulatory and pro-angiogenic tetrapeptide derived from the N-terminal end of thymosin β4 (Tβ4 aa 1-4) via sequential enzymatic actions of meprin-α and prolyl-oligopeptidase (POP), while angiotensin converting enzyme (ACE) mediates Ac-SDKP degradation. In animal heart, kidney and brain injury studies, Ac-SDKP ameliorates end-organ damage by promoting angiogenesis, as well as by reducing inflammation and fibrosis.
Thymosin β4 (Tβ4)-derived immunomodulatory and pro-angiogenic peptide with in vivo anti-inflammatory and anti-fibrotic efficacy.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持