SML3665
Palosuran
≥98% (HPLC)
别名:
1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea, CT-058362
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关于此项目
经验公式（希尔记法）:
C25H30N4O2
化学文摘社编号:
分子量:
418.53
UNSPSC Code:
12352200
NACRES:
NA.25
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
SMILES string
N3(CCC(CC3)(O)Cc4ccccc4)CCNC(=O)Nc1c2c(nc(c1)C)cccc2
InChI
1S/C25H30N4O2/c1-19-17-23(21-9-5-6-10-22(21)27-19)28-24(30)26-13-16-29-14-11-25(31,12-15-29)18-20-7-3-2-4-8-20/h2-10,17,31H,11-16,18H2,1H3,(H2,26,27,28,30)
InChI key
WYJCYXOCHXWTHG-UHFFFAOYSA-N
Biochem/physiol Actions
Orally available, potent, and selective noncompetitive urotensin 2 receptor antagonist
Palosuran (ACT-058362) is an orally available, potent, and selective noncompetitive urotensin 2 receptor antagonist. Palosuran decreases serum glucose, cholesterol, and triglyceride levels and increases survival in a rat model of diabetes induced by streptozotocin.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable