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Merck
CN

SML3906

CNS-11

≥98% (HPLC)

别名:

3-Oxo-N-(2,4,6-trimethylphenyl)indeno[1,2,3-de]phthalazine-2(3H)-acetamid, N-mesityl-2-(3-oxoindeno[1,2,3-de]phthalazin-2(3H)-yl)acetamide

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关于此项目

经验公式(希尔记法):
C25H21N3O2
化学文摘社编号:
分子量:
395.45
UNSPSC Code:
12352200
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (Warmed)

storage temp.

2-8°C

SMILES string

O=C1C2=C(C(C3=C4C=CC=C3)=NN1CC(NC5=C(C)C=C(C)C=C5C)=O)C4=CC=C2

InChI key

MVMNMAWCMNMLEC-UHFFFAOYSA-N

Biochem/physiol Actions

Brain tissue penetrant alpha-synuclein ligand that potently disaggregate alpha-synuclein fibrils in vitro and in vivo models.



CNS-11 is brain tissue penetrant alpha-synuclein ligand that potently disaggregate alpha-synuclein fibrils in vitro and in vivo models. CNS-11 inhibits intracellular seeding of a-synuclein fibrils in biosensor cells—HEK293T cells. C-11 reduces number of a-synuclein aggregates in C. elegans model.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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