SML3980
HHS-465 10% solution in DMSO
≥98% (HPLC)
别名:
N-2-Propyn-1-yl-4-(2H-1,2,3-triazol-2-ylsulfonyl)benzamide 10% solution in DMSO
质量水平
方案
≥98% (HPLC)
表单
(10% Solution in DMSO)
储存条件
(Material decomposes above 90°C, keep below 40°C during handling)
颜色
white to beige
运输
wet ice
储存温度
-10 to -25°C
生化/生理作用
Cell penetrant tyrosine/lysine-reactive (Y-and K-reactive) sulfonyl-triazole exchange (SuTEx) probe.
HHS-465 is a cell penetrant tyrosine/lysine-reactive (Y-and K-reactive) sulfonyl-triazole exchange (SuTEx) probe suitable to study novel nucleophilic sites on established and poorly described protein targets.
HHS-465 is a cell penetrant tyrosine/lysine-reactive (Y-and K-reactive) sulfonyl-triazole exchange (SuTEx) probe suitable to study novel nucleophilic sites on established and poorly described protein targets.
法规信息
新产品
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历史批次信息供参考:
Development and biological applications of sulfur-triazole exchange (SuTEx) chemistry.
Borne AL, et al.
RSC Chemical Biology, 2, 322-337 (2021)
Anthony M Ciancone et al.
Cell chemical biology, 29(12), 1709-1720 (2022-12-09)
RNA granules are cytoplasmic condensates that organize biochemical and signaling complexes in response to cellular stress. Functional proteomic investigations under RNA-granule-inducing conditions are needed to identify protein sites involved in coupling stress response with ribonucleoprotein regulation. Here, we apply chemical
Heung Sik Hahm et al.
Nature chemical biology, 16(2), 150-159 (2019-11-27)
Covalent probes serve as valuable tools for global investigation of protein function and ligand binding capacity. Despite efforts to expand coverage of residues available for chemical proteomics (e.g., cysteine and lysine), a large fraction of the proteome remains inaccessible with
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