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Merck
CN

SML3980

HHS-465 10% solution in DMSO

≥98% (HPLC)

别名:

N-2-Propyn-1-yl-4-(2H-1,2,3-triazol-2-ylsulfonyl)benzamide 10% solution in DMSO

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关于此项目

经验公式（希尔记法）:
C12H10N4O3S
分子量:
290.30
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
(10% Solution in DMSO)
Quality level:
100
Storage condition:
(Material decomposes above 90°C, keep below 40°C during handling)

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assay

≥98% (HPLC)

form

(10% Solution in DMSO)

storage condition

(Material decomposes above 90°C, keep below 40°C during handling)

color

white to beige

shipped in

wet ice

storage temp.

-10 to -25°C

Quality Level

100

Biochem/physiol Actions

Cell penetrant tyrosine/lysine-reactive (Y-and K-reactive) sulfonyl-triazole exchange (SuTEx) probe.
HHS-465 is a cell penetrant tyrosine/lysine-reactive (Y-and K-reactive) sulfonyl-triazole exchange (SuTEx) probe suitable to study novel nucleophilic sites on established and poorly described protein targets.

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000436222
0000436222

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Development and biological applications of sulfur-triazole exchange (SuTEx) chemistry.
Borne AL, et al.
RSC Chemical Biology, 2, 322-337 (2021)
Anthony M Ciancone et al.
Cell chemical biology, 29(12), 1709-1720 (2022-12-09)
RNA granules are cytoplasmic condensates that organize biochemical and signaling complexes in response to cellular stress. Functional proteomic investigations under RNA-granule-inducing conditions are needed to identify protein sites involved in coupling stress response with ribonucleoprotein regulation. Here, we apply chemical
Heung Sik Hahm et al.
Nature chemical biology, 16(2), 150-159 (2019-11-27)
Covalent probes serve as valuable tools for global investigation of protein function and ligand binding capacity. Despite efforts to expand coverage of residues available for chemical proteomics (e.g., cysteine and lysine), a large fraction of the proteome remains inaccessible with

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