Quality Level
assay
≥98% (HPLC)
form
(10% Solution in DMSO)
storage condition
(Material decomposes above 90°C, keep below 40°C during handling)
color
white to beige
shipped in
wet ice
storage temp.
-10 to -25°C
SMILES string
O=S(N1N=CC=N1)(C2=CC=C(C(NCC#C)=O)C=C2)=O
Biochem/physiol Actions
Cell penetrant tyrosine/lysine-reactive (Y-and K-reactive) sulfonyl-triazole exchange (SuTEx) probe.
HHS-465 is a cell penetrant tyrosine/lysine-reactive (Y-and K-reactive) sulfonyl-triazole exchange (SuTEx) probe suitable to study novel nucleophilic sites on established and poorly described protein targets.
HHS-465 is a cell penetrant tyrosine/lysine-reactive (Y-and K-reactive) sulfonyl-triazole exchange (SuTEx) probe suitable to study novel nucleophilic sites on established and poorly described protein targets.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
188.6 °F - closed cup
flash_point_c
87 °C - closed cup
法规信息
新产品
此项目有
Development and biological applications of sulfur-triazole exchange (SuTEx) chemistry.
Borne AL, et al.
RSC Chemical Biology, 2, 322-337 (2021)
Anthony M Ciancone et al.
Cell chemical biology, 29(12), 1709-1720 (2022-12-09)
RNA granules are cytoplasmic condensates that organize biochemical and signaling complexes in response to cellular stress. Functional proteomic investigations under RNA-granule-inducing conditions are needed to identify protein sites involved in coupling stress response with ribonucleoprotein regulation. Here, we apply chemical
Heung Sik Hahm et al.
Nature chemical biology, 16(2), 150-159 (2019-11-27)
Covalent probes serve as valuable tools for global investigation of protein function and ligand binding capacity. Despite efforts to expand coverage of residues available for chemical proteomics (e.g., cysteine and lysine), a large fraction of the proteome remains inaccessible with
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SML3980-250UL | 04065272487627 |
| SML3980-50UL | 04065272487634 |