SML4067
MCLA Hydrochloride
≥98% (HPLC)
别名:
2-Methyl-6-(p-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one HCl, 3,7-Dihydro-2-methyl-6-(4-methoxyphenyl)imidazol[1,2-a]pyrazine-3-one HCl, 6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one HCl, 6-(4-Methoxyphenyl)-2-methylimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride, MCLA HCl
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
, Faint yellow to very dark orange
溶解性
DMSO: 2 mg/mL, clear (Warmed)
储存温度
2-8°C
SMILES字符串
O=C1C(C)=NC2=CNC(C3=CC=C(OC)C=C3)=CN21.Cl
生化/生理作用
Chemiluminescence probe, after glow substrate, known for its high sensitivity in detecting reactive oxygen species like superoxide anion and singlet oxygen, both intracellularly and extracellularly.
MCLA (methoxylated Cypridina luciferin analog) is a highly sensitive probe employed in the detection of reactive oxygen species (ROS), particularly superoxide anion (O2•−) and singlet oxygen (1O2). It is notable for its blue luminescence (~ 455 nm), which is a critical indicator in ROS detection. MCLA′s detection mechanism involves oxidation to a probe radical, which then reacts with O2•− to produce luminescence. MCLA offers a broad dynamic range, making it versatile for both intracellular measurements in live cells and extracellular detection in various sample types. Its application is particularly significant in research related to oxidative stress, inflammation, and neurodegenerative diseases, where ROS play a pivotal role. Ex: ~ 430 nm, Em: ~ 549 nm.
MCLA (methoxylated Cypridina luciferin analog) is a highly sensitive probe employed in the detection of reactive oxygen species (ROS), particularly superoxide anion (O2•−) and singlet oxygen (1O2). It is notable for its blue luminescence (~ 455 nm), which is a critical indicator in ROS detection. MCLA′s detection mechanism involves oxidation to a probe radical, which then reacts with O2•− to produce luminescence. MCLA offers a broad dynamic range, making it versatile for both intracellular measurements in live cells and extracellular detection in various sample types. Its application is particularly significant in research related to oxidative stress, inflammation, and neurodegenerative diseases, where ROS play a pivotal role. Ex: ~ 430 nm, Em: ~ 549 nm.
免责声明
Hygroscopic
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
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