SML4103
4-Hydroperoxycyclophosphamide
≥98% (HPLC)
别名:
2-[Bis(2-chloroethyl)amino]tetrahydro-2-oxido-2H-1,3,2-oxazaphosphorin-4-yl hydroperoxide, 4-Hydroperoxycyclofosfamide, 4-OOH-CY, Asta 6496, Perfosfamide
生化/生理作用
Active metabolite of the nitrogen mustard cyclophosphamide.
4-Hydroperoxycyclophosphamide is the active metabolite of the nitrogen mustard cyclophosphamide. 4-Hydroperoxycyclophosphamide exhibits potent antineoplastic and immunosuppressive activities.
4-Hydroperoxycyclophosphamide is the active metabolite of the nitrogen mustard cyclophosphamide. 4-Hydroperoxycyclophosphamide exhibits potent antineoplastic and immunosuppressive activities.
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Muta. 1B - Repr. 1A - Skin Corr. 1B - Skin Sens. 1A
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Xinfei Ma et al.
Life sciences, 274, 119331-119331 (2021-03-16)
Cyclophosphamide (CP) is a common therapeutic drug for cancer, but exposure to CP can cause acute hepatotoxicity. This study aimed to elucidate the protective effects of Ligustrazine (2, 3, 5, 6-tetramethylpyrazine, TMP) on hepatotoxicity induced by CP or its active
Charles Linker
Best practice & research. Clinical haematology, 20(1), 77-84 (2007-03-06)
Since 1986, the University of California San Francisco has developed novel approaches to autologous transplantation for acute myeloid leukemia (AML). Strategies have included intensive preparative regimens using busulfan and etoposide, and evolving strategies for pre-transplant consolidation and stem cell collection.
I Piccini et al.
The British journal of dermatology, 186(1), 129-141 (2021-09-09)
Permanent chemotherapy-induced alopecia (pCIA), for which preventive interventions remain limited, can manifest with scarring. While the underlying pathomechanisms of pCIA are unclear, depletion of epithelial hair follicle (HF) stem cells (eHFSCs) is likely to play a role. To explore the
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