SML4181
Sulbactam sodium

≥98% (HPLC), powder, β-lactamase inhibitor
别名:
CP 45899-2, Sodium (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide, (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide sodium salt, Penicillanic acid 1,1-dioxide sodium salt, Sodium 1,1-dioxypenicillanate, Sodium penicillanate 1,1-dioxide
质量水平
方案
≥98% (HPLC)
表单
powder
储存条件
desiccated
颜色
white to beige
溶解性
H2O: 2 mg/mL, clear
储存温度
-10 to -25°C
SMILES字符串
O=C([C@@H]1N2[C@]([H])(S(=O)(C1(C)C)=O)CC2=O)O[Na]
应用
Sulbactam sodium may be used for in vitro antibacterial efficacy analysis.
生化/生理作用
Sulbactam is a competitive, irreversible β-lactamase inhibitor that enhances β-lactam antibiotics′ efficacy.
Sulbactam sodium, the sodium salt form of sulbactam, is water-soluble and exhibits enhanced hydrophilicity and is better suited for formulations involving aqueous media. In its capacity as a β-lactamase inhibitor, sulbactam sodium synergistically augments the antimicrobial efficacy of β-lactam antibiotics against recalcitrant bacterial pathogens. This synergistic effect is achieved through an irreversible covalent interaction between sulbactam and the β-lactamase enzymes, which are responsible for the degradation and consequent inactivation of β-lactam antibiotics. Additionally, sulbactam sodium demonstrates inherent antibacterial activity, albeit with a relatively lower potency compared to other members of the β-lactam antibiotic class.
Sulbactam sodium, the sodium salt form of sulbactam, is water-soluble and exhibits enhanced hydrophilicity and is better suited for formulations involving aqueous media. In its capacity as a β-lactamase inhibitor, sulbactam sodium synergistically augments the antimicrobial efficacy of β-lactam antibiotics against recalcitrant bacterial pathogens. This synergistic effect is achieved through an irreversible covalent interaction between sulbactam and the β-lactamase enzymes, which are responsible for the degradation and consequent inactivation of β-lactam antibiotics. Additionally, sulbactam sodium demonstrates inherent antibacterial activity, albeit with a relatively lower potency compared to other members of the β-lactam antibiotic class.
免责声明
Hygroscopic Store with desiccant
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历史批次信息供参考:
分析证书(COA)
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