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SML4186

Levofloxacin hydrochloride

≥98% (HPLC), powder, DNA gyrase and topoisomerase IV inhibitor

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关于此项目

经验公式(希尔记法):
C18H20FN3O4 · xHCl
化学文摘社编号:
分子量:
361.37 (free base basis)
MDL number:
NACRES:
NA.21
UNSPSC Code:
41116107
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

O=C1C2=CC(F)=C(C3=C2N([C@H](CO3)C)C=C1C(O)=O)N4CCN(C)CC4.[xHCl]

General description

Levofloxacin is the L-isomer of the racemic fluoroquinolone, ofloxacin. It has a more intricate fused ring structure that is linked to the oxazinoquinoline core as compared to quinolones. Levofloxacin is a broad-spectrum fluoroquinolone antibiotic that exhibits high water solubility. While the hydrochloride form of levofloxacin is freely soluble in water, levofloxacin itself is only sparingly soluble in aqueous solutions.

Application

Levofloxacin hydrochloride may be used to:
  • investigate its antibacterial effects against Gram-positive and Gram-negative bacteria
  • assess environmental antibiotic pollution
  • study drug–food interactions in pharmacokinetic research by evaluating the impact of dietary interventions on quinolone bioavailability

Biochem/physiol Actions

Levofloxacin is a fluoroquinolone antibiotic with broad-spectrum activity, the optical S-(-) isomer of ofloxacin, which kills bacteria by blocking DNA gyrase and type IV topoisomerase—critical enzymes for DNA replication and transcription—leading to cell death. It is effective against a broad array of both Gram-positive and Gram-negative bacteria, in addition to Mycoplasmas.

Disclaimer

Hygroscopic Store with desiccant


pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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