SRP4248
MIP-1beta from mouse
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
别名:
CCL4, MIP-1- β, Macrophage inflammatory protein 1-β, Small inducible cytokine A4, T-cell activation protein 2
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关于此项目
Form:
lyophilized
Assay:
≥98% (HPLC), ≥98% (SDS-PAGE)
Biological source:
mouse
Recombinant:
expressed in E. coli
Mol wt:
~7.8 kDa
biological source
mouse
recombinant
expressed in E. coli
assay
≥98% (HPLC), ≥98% (SDS-PAGE)
form
lyophilized
mol wt
~7.8 kDa
packaging
pkg of 10 μg
impurities
endotoxin, tested
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Ccl4(20303)
General description
Mouse macrophage inflammatory protein-1β (MIP-1β) is a 7.8 kDa protein containing 69 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue macrophages.
MIP-1β is mainly generated by monocytes and lymphocytes. It is a member of CC family of chemokine intercrine cytokine. MIP-1β shares 70% similarity with MIP-1α. It is localized to a number of tissues such as smooth muscles, monocytes, neutrophils, mast cells, fibroblast B and T lymphocytes.
MIP-1β is mainly generated by monocytes and lymphocytes. It is a member of CC family of chemokine intercrine cytokine. MIP-1β shares 70% similarity with MIP-1α. It is localized to a number of tissues such as smooth muscles, monocytes, neutrophils, mast cells, fibroblast B and T lymphocytes.
Biochem/physiol Actions
Macrophage inflammatory protein-1 β (MIP-1β) promotes myelopoietic cellular growth and induces leukocyte chemoattraction. MIP-1β is an effective HIV infection suppressor.
Physical form
Lyophilized without any additives.
Preparation Note
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers.
法规信息
新产品
此项目有
Atlas of immunology, 318-318 (2003)
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