biological source
human
recombinant
expressed in E. coli
assay
≥70% (SDS-PAGE)
form
buffered aqueous glycerol solution
mol wt
~90 kDa
NCBI accession no.
application(s)
cell analysis
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... SMAD2(4087)
Physical form
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation Note
after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles
存储类别
10 - Combustible liquids
wgk
WGK 1
法规信息
常规特殊物品
此项目有
相关内容
Instructions
Targeting the transforming growth factor-beta signaling pathway in human cancer.
Nagaraj NS
Expert Opinion on Investigational Drugs (2010)
Signaling of transforming growth factor-beta family members through Smad proteins.
Itoh S
European Journal of Biochemistry (2000)
M Funaba et al.
Molecular endocrinology (Baltimore, Md.), 14(10), 1583-1591 (2000-10-24)
Smads mediate activin, transforming growth factor beta (TGFbeta), and bone morphogenetic protein signaling from receptors to nuclei. According to the current model, activated activin/TGFbeta receptors phosphorylate the carboxyl-terminal serines of Smad2 and Smad3 (SSMS-COOH); phosphorylated Smad2/3 oligomerizes with Smad4, translocates
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SRP5131-50UG | 04061832942490 |