Name: Valpromide
Brand: SIGMA

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About This Item

经验公式（希尔记法）:

C₈H₁₇NO

CAS Number:

2430-27-5

分子量:

143.23

MDL编号:

MFCD00051534

UNSPSC代码:

12352200

PubChem化学物质编号:

329829044

NACRES:

NA.77

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质量水平

100

方案

≥97% (NMR)

表单

powder

颜色

white to off-white

溶解性

DMSO: >10 mg/mL

创始人

Sanofi Aventis

储存温度

room temp

SMILES字符串

CCCC(CCC)C(N)=O

InChI

1S/C8H17NO/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H2,9,10)

InChI key

OMOMUFTZPTXCHP-UHFFFAOYSA-N

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应用

Valpromide has been used to pretreat NIH/3T3 cells to test its effect on cytomegalovirus (CMV) viral replication. It has also been used to test its antiviral functionality in herpes simplex virus type 1 (HSV-1) infected human oligodendroglioma (HOG) cells. It may be used to test its effect on apoptosis induction in astrocytes.

生化/生理作用

Valpromide (VPD) is a derivative of valproic acid (VPA) and is used as an antiepileptic drug.

Valpromide (VPD) is a derivative of valproic acid (VPA) and is used as an antiepileptic drug. It is hydrolyzed quickly to VPA in vivo, but has intrinsic anticonvulsant activity.

Valpromide possesses antipsychotic property. It lacks the toxic and teratogenic effects of valproic acid. It also lacks the histone deacetylase (HDAC) inhibitory activity of valproic acid.