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Merck
CN

V9130

N-香草基壬酰胺

≥97%, nicotinamide adenine dinucleotide phosphate inhibitor, powder

别名:

N-香草基壬酰胺, N-(4-羟基-3-甲氧基苄基)壬酰胺, 伪辣椒素, 合成辣椒素, 壬酸香草酰胺, 香草壬酰胺

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关于此项目

经验公式(希尔记法):
C17H27NO3
化学文摘社编号:
分子量:
293.40
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
219-484-1
MDL number:
Beilstein/REAXYS Number:
2144300
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产品名称

N-香草基壬酰胺, ≥97%, powder

InChI

1S/C17H27NO3/c1-3-4-5-6-7-8-9-17(20)18-13-14-10-11-15(19)16(12-14)21-2/h10-12,19H,3-9,13H2,1-2H3,(H,18,20)

InChI key

RGOVYLWUIBMPGK-UHFFFAOYSA-N

SMILES string

CCCCCCCCC(=O)NCc1ccc(O)c(OC)c1

assay

≥97%

form

powder

color

white to off-white

solubility

methanol: 100 mg/mL, clear to slightly hazy, colorless to deep brown-yellow

storage temp.

2-8°C

Quality Level

Gene Information

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General description

N-Vanillylnonanamide has antifouling properties. It acts as an nicotinamide adenine dinucleotide phosphate (NADPH) inhibitor.

Application

N-Vanillylnonanamide has been used for the preparation of spicules. It has also been used to reduce the firing of most extrinsic sensory axons.

Other Notes

Synthetic analogue of capsaicin with similar bioactivity.

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

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Lot/Batch Number

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Sphingolipids in Disease (2013)
Measurement of strains experienced by viscerofugal nerve cell bodies during mechanosensitive firing using digital image correlation
Palmer G, et al.
American Journal of Physiology. Heart and Circulatory Physiology (2016)
Coping with Biological Growth on Stone Heritage Objects: Methods, Products, Applications, and Perspectives (2017)
R Ando et al.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 91(1), 55-59 (1988-01-01)
Effects of cysteamine (2-mercaptoethylamine) on vocalization responses, a parameter of nociceptive response, was studied in conscious guinea pigs. Intra-arterial injection of bradykinin (3 micrograms), acetylcholine (300 micrograms), capsaicin (3 micrograms) and vanillyl n-nonoylamide (3 micrograms, VNA) induced severe vocalization responses.
G B Kasting et al.
Journal of pharmaceutical sciences, 86(1), 142-146 (1997-01-01)
The percutaneous absorption of three highly lipophilic analogs of capsaicin--vanillylnonanamide (VN), olvanil, and NE-21610--was measured in vivo in the CD:VAF rat, and in vitro through excised CD: VAF and SkH:Fz rat skin and human cadaver skin. Absorption and skin metabolism

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