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经验公式(希尔记法):
C17H27NO3
化学文摘社编号:
分子量:
293.40
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
219-484-1
MDL number:
Beilstein/REAXYS Number:
2144300
产品名称
N-香草基壬酰胺, ≥97%, powder
InChI
1S/C17H27NO3/c1-3-4-5-6-7-8-9-17(20)18-13-14-10-11-15(19)16(12-14)21-2/h10-12,19H,3-9,13H2,1-2H3,(H,18,20)
InChI key
RGOVYLWUIBMPGK-UHFFFAOYSA-N
SMILES string
CCCCCCCCC(=O)NCc1ccc(O)c(OC)c1
assay
≥97%
form
powder
color
white to off-white
solubility
methanol: 100 mg/mL, clear to slightly hazy, colorless to deep brown-yellow
storage temp.
2-8°C
Quality Level
Gene Information
rat ... Trpv1(83810), Trpv4(66026)
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General description
N-Vanillylnonanamide has antifouling properties. It acts as an nicotinamide adenine dinucleotide phosphate (NADPH) inhibitor.
Application
N-Vanillylnonanamide has been used for the preparation of spicules. It has also been used to reduce the firing of most extrinsic sensory axons.
Other Notes
Synthetic analogue of capsaicin with similar bioactivity.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
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Palmer G, et al.
American Journal of Physiology. Heart and Circulatory Physiology (2016)
Coping with Biological Growth on Stone Heritage Objects: Methods, Products, Applications, and Perspectives (2017)
R Ando et al.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 91(1), 55-59 (1988-01-01)
Effects of cysteamine (2-mercaptoethylamine) on vocalization responses, a parameter of nociceptive response, was studied in conscious guinea pigs. Intra-arterial injection of bradykinin (3 micrograms), acetylcholine (300 micrograms), capsaicin (3 micrograms) and vanillyl n-nonoylamide (3 micrograms, VNA) induced severe vocalization responses.
G B Kasting et al.
Journal of pharmaceutical sciences, 86(1), 142-146 (1997-01-01)
The percutaneous absorption of three highly lipophilic analogs of capsaicin--vanillylnonanamide (VN), olvanil, and NE-21610--was measured in vivo in the CD:VAF rat, and in vitro through excised CD: VAF and SkH:Fz rat skin and human cadaver skin. Absorption and skin metabolism
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