WH0221037M3
Monoclonal Anti-JMJD1C antibody produced in mouse
clone 5F12, purified immunoglobulin, buffered aqueous solution
别名:
Anti-DKFZp761F0118, Anti-FLJ14374, Anti-KIAA1380, Anti-RP1110C13.2, Anti-TRIP8, Anti-jumonji domain containing 1C
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
5F12, monoclonal
Application:
ELISA (i), IHC (p), WB
Citations:
5
biological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
5F12, monoclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, indirect ELISA: suitable, western blot: 1-5 μg/mL
isotype
IgG2aκ
GenBank accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... JMJD1C(221037)
General description
Jumonji domain containing 1C (JMJD1C) belongs to the lysine demethylase 3 family and maybe a histone demethylase. The gene encoding it is localized on human chromosome 10q21.3.
Immunogen
JMJD1C (NP_004232, 2 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
IVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSD
Sequence
IVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSD
Biochem/physiol Actions
Jumonji domain containing 1C (JMJD1C) takes part in DNA-damage repair. It is a coactivator of the androgen receptor and also associates with the thyroid receptor. JMJD1C activates a transcription factor involved in acute myeloid leukemia. It has been linked to fatty liver disease and thyroiditis.
Physical form
Solution in phosphate buffered saline, pH 7.4
Legal Information
GenBank is a registered trademark of United States Department of Health and Human Services
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)