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Merck
CN

47775

Supelco

甲萘醌 (K3)

analytical standard

别名:

甲萘醌, 2-甲基-1,4-萘醌, 维生素 K3

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关于此项目

经验公式(希尔记法):
C11H8O2
CAS Number:
分子量:
172.18
Beilstein:
1908453
EC 号:
MDL编号:
UNSPSC代码:
12164500
PubChem化学物质编号:
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等级

analytical standard

质量水平

CofA

current certificate can be downloaded

特点

standard type fat soluble vitamin

包装

ampule of 1000 mg

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

105-107 °C (lit.)

应用

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

包装形式

neat

储存温度

2-30°C

SMILES字符串

CC1=CC(=O)c2ccccc2C1=O

InChI

1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3

InChI key

MJVAVZPDRWSRRC-UHFFFAOYSA-N

基因信息

human ... NQO1(1728)

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一般描述

甲萘醌是一种促血栓形成的化合物,属于维生素K类化合物,其对于凝血酶原和其他凝血因子的生物合成是必不可少的。它可用作细胞培养和体内研究中的模型醌。 它是叶绿醌的分解代谢产物,是大鼠组织中甲萘醌4的循环前体。
甲萘醌(K3)是一种脂溶性维生素前体,它是肠中口服叶绿醌(维生素k1)的分解代谢产物。

应用

有关合适仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务部门。
甲萘醌(K3)可用作液相色谱技术定量测定生物体液中分析物的分析参考标准品。

象形图

Exclamation markEnvironment

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Development of a validated liquid chromatography method for the simultaneous determination of eight fat-soluble vitamins in biological fluids after solid-phase extraction
Chatzimichalakis FP, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 805(2), 289-296 (2004)
Arne Søraas et al.
Journal of oral microbiology, 6 (2014-09-11)
The prevalence of infections caused by Cefotaximase-Munich (CTX-M)-type extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) has rapidly increased during the past 15 years. Enterobacteriaceae are commonly found in the gastrointestinal tract and long-term intestinal carriage is considered important for the spread of ESBL
Daiki Habu et al.
JAMA, 292(3), 358-361 (2004-07-22)
Previous findings indicate that vitamin K2 (menaquinone) may play a role in controlling cell growth. To determine whether vitamin K2 has preventive effects on the development of hepatocellular carcinoma in women with viral cirrhosis of the liver. Forty women diagnosed
H H Thijssen et al.
The British journal of nutrition, 75(1), 121-127 (1996-01-01)
We measured the vitamin K status in postmortem human tissues (brain, heart, kidney, liver, lung, pancreas) to see if there is a tissue-specific distribution pattern. Phylloquinone (K1) was recovered in all tissues with relatively high levels in liver, heart and
Kerry Routenberg Love et al.
Nature chemical biology, 3(11), 697-705 (2007-10-20)
The addition of ubiquitin (Ub) and ubiquitin-like (Ubl) modifiers to proteins serves to modulate function and is a key step in protein degradation, epigenetic modification and intracellular localization. Deubiquitinating enzymes and Ubl-specific proteases, the proteins responsible for the removal of

实验方案

Separation of (±)-α-Tocopherol, analytical standard; Menadione (K3), analytical standard; (+)-γ-Tocopherol, analytical standard; Cholecalciferol (D3), analytical standard

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