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Merck
CN

47794

1,2,3-三氯丙烷

analytical standard

别名:

Trichlorohydrin, 三氯丙烷

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关于此项目

线性分子式:
CH2ClCHClCH2Cl
化学文摘社编号:
分子量:
147.43
Beilstein:
1732068
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.24
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等级

analytical standard

质量水平

CofA

current certificate can be downloaded

包装

ampule of 1000 mg

技术

HPLC: suitable
gas chromatography (GC): suitable

折射率

n20/D 1.484 (lit.)

沸点

156 °C (lit.)

mp

−14 °C (lit.)

密度

1.387 g/mL at 25 °C (lit.)

应用

cleaning products
cosmetics
environmental
food and beverages
personal care

包装形式

neat

储存温度

2-30°C

SMILES字符串

ClCC(Cl)CCl

InChI

1S/C3H5Cl3/c4-1-3(6)2-5/h3H,1-2H2

InChI key

CFXQEHVMCRXUSD-UHFFFAOYSA-N

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一般描述

This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Repr. 1B - STOT RE 1 Inhalation

靶器官

Kidney,Liver,Mucous membranes

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

165.2 °F - DIN 51758

闪点(°C)

74 °C - DIN 51758

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Alena Stsiapanava et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 67(Pt 2), 253-257 (2011-02-09)
Haloalkane dehalogenases make up an important class of hydrolytic enzymes which catalyse the cleavage of carbon-halogen bonds in halogenated aliphatic compounds. There is growing interest in these enzymes owing to their potential use in environmental and industrial applications. The haloalkane
Alexandra J Salter-Blanc et al.
Environmental science & technology, 45(9), 4073-4079 (2011-04-14)
The reactivity of zerovalent zinc (ZVZ) toward 1,2,3-trichloropropane (TCP) was evaluated under a variety of solution conditions, including deionized water, groundwater, and artificial groundwater, over a pH range of about 6.5-12. In deionized water, first-order rate constants for TCP disappearance
Martina Pavlova et al.
Nature chemical biology, 5(10), 727-733 (2009-08-25)
Engineering enzymes to degrade anthropogenic compounds efficiently is challenging. We obtained Rhodococcus rhodochrous haloalkane dehalogenase mutants with up to 32-fold higher activity than wild type toward the toxic, recalcitrant anthropogenic compound 1,2,3-trichloropropane (TCP) using a new strategy. We identified key
Marta Monincová et al.
Applied and environmental microbiology, 73(6), 2005-2008 (2007-01-30)
1,2,3-Trichloropropane (TCP) is a highly toxic and recalcitrant compound. Haloalkane dehalogenases are bacterial enzymes that catalyze the cleavage of a carbon-halogen bond in a wide range of organic halogenated compounds. Haloalkane dehalogenase LinB from Sphingobium japonicum UT26 has, for a
Pavel Banás et al.
Journal of computer-aided molecular design, 20(6), 375-383 (2006-10-04)
1,2,3-Trichloropropane (TCP) is a highly toxic, recalcitrant byproduct of epichlorohydrin manufacture. Haloalkane dehalogenase (DhaA) from Rhodococcus sp. hydrolyses the carbon-halogen bond in various halogenated compounds including TCP, but with low efficiency (k (cat)/K (m )= 36 s(-1) M(-1)). A Cys176Tyr-DhaA

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