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Merck
CN

V000702

过氧化苯甲酰

72.0-80.0%

别名:

过氧化二苯甲酰

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关于此项目

线性分子式:
(C6H5CO)2O2
化学文摘社编号:
分子量:
242.23
PubChem Substance ID:
Beilstein/REAXYS Number:
984320
MDL number:
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InChI key

OMPJBNCRMGITSC-UHFFFAOYSA-N

SMILES string

O=C(OOC(=O)c1ccccc1)c2ccccc2

InChI

1S/C14H10O4/c15-13(11-7-3-1-4-8-11)17-18-14(16)12-9-5-2-6-10-12/h1-10H

grade

synthesis grade

assay

72.0-80.0%

autoignition temp.

176 °F

mp

105 °C (lit.)

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Application

聚合工艺中广泛应用的引发剂、固化剂和交联剂。

pictograms

Exclamation markEnvironment

signalword

Warning

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Sens. 1

存储类别

4.1A - Other explosive hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Emil A Tanghetti et al.
Dermatologic clinics, 27(1), 17-24 (2008-11-06)
Benzoyl peroxide (BPO) is the most widely used topical acne treatment, with significant antibacterial, antikeratolytic, and comedolytic activity. It has been shown to be extremely effective as monotherapy and in combination with antibiotics or retinoids for managing comedonal and inflammatory
A L Kraus et al.
Regulatory toxicology and pharmacology : RTP, 21(1), 87-107 (1995-02-01)
Topical benzoyl peroxide has been used in the treatment of acne for over 30 years, with no reports of adverse effects that could be related to skin carcinogenesis. Two case-control epidemiological studies have found a lack of association between the
Tarek Fakhouri et al.
Journal of drugs in dermatology : JDD, 8(7), 657-661 (2009-07-11)
Antibiotic resistance of Propionibacterium acnes (P. acnes) is a growing phenomenon in the wake of widespread use of topical and systemic antibiotics for acne vulgaris. Benzoyl peroxide has a proven track record of safety and efficacy, and can decrease reliance
Kate McKeage et al.
American journal of clinical dermatology, 9(3), 193-204 (2008-04-24)
Clindamycin 1%/benzoyl peroxide 5% (BenzaClin) is a combination gel indicated for use twice daily, or as directed by a physician, for the topical treatment of inflammatory and noninflammatory lesions of acne vulgaris. In well designed clinical trials in patients with
Gillian M Keating
American journal of clinical dermatology, 12(6), 407-420 (2011-10-05)
Adapalene 0.1%/benzoyl peroxide 2.5% gel (Epiduo™, Tactuo™) is the only fixed-dose combination product available that combines a topical retinoid with benzoyl peroxide; it targets three of the four main pathophysiologic factors in acne. This article reviews the therapeutic efficacy and

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