等级
puriss.
方案
98.0%
mp
251 °C (dec.) (lit.)
SMILES字符串
OC(=O)c1cc(O)c(O)c(O)c1
InChI
1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12)
InChI key
LNTHITQWFMADLM-UHFFFAOYSA-N
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生化/生理作用
没食子酸是一种水溶性酚酸，存在于葡萄和许多植物的叶子中。 没食子酸酯，如单宁、儿茶素没食子酸酯和脂肪族没食子酸酯，是有效的 体外抗氧化剂。 但是，没食子酸本身在 体外也具有抗氧化、抗癌和抗血管生成活性。
Gallic acid has an ability to induce apoptosis in promyelocytic leukemia HL-60RG cells. In addition, it also exhibits anti- inflammatory, anti-microbial and radical scavenging activities in- vitro. Gallic acid prevents mast cell-derived inflammatory allergic reactions by inhibiting histamine secretion and pro-inflammatory cytokine expression. Thus, this phenolic acid can be used as a potent therapeutic to treat inflammatory allergic diseases.
Gallic acid is a water soluble phenolic acid present in grapes and in the leaves of many plants. Gallic acid esters, such as tannins, catechin gallates and aliphatic gallates are potent antioxidants in vitro. However, gallic acid itself also appears to have antioxidant, anticarcinogenic and antiangiogenic activity in vitro.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Gallic Acid Inhibits Histamine Release and Pro-inflammatory Cytokine Production in Mast Cells
Kim S H, et al.
Toxicological Sciences, 91(1), 123-131 (2005)
Anti-Inflammatory Activity of Gallic Acid
Kroes B V, et al.
Planta Medica, 58(06), 499-504 (1992)
Antioxidant, Gallic Acid, Induces Apoptosis in HL-60RG Cells
Inoue M, et al.
Biochemical and Biophysical Research Communications, 204(2), 898-904 (1994)
Plant polyphenols (vegetable tannins): gallic acid metabolism.
E Haslam et al.
Natural product reports, 11(1), 41-66 (1994-01-01)
T R Aguiar et al.
Journal of dental research, 93(4), 417-422 (2014-02-28)
Although proanthocyanidins (PACs) modify dentin, the effectiveness of different PAC sources and the correlation with their specific chemical composition are still unknown. This study describes the chemical profiling of natural PAC-rich extracts from 7 plants using ultra high pressure/performance liquid
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