产品名称
L-肌肽, Vetec™, reagent grade, 98%
grade
reagent grade
product line
Vetec™
assay
98%
form
powder
color
white to off-white
mp
253 °C (dec.) (lit.)
storage temp.
−20°C
SMILES string
NCCC(=O)N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI
1S/C9H14N4O3/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6/h4-5,7H,1-3,10H2,(H,11,12)(H,13,14)(H,15,16)/t7-/m0/s1
InChI key
CQOVPNPJLQNMDC-ZETCQYMHSA-N
Biochem/physiol Actions
L-肌肽一种二肽，以毫摩尔浓度存在于脑、肌肉和眼睛晶状体中。 在模型系统中，它是一种有效的抗氧化剂，可清除氧自由基和过渡金属离子。 它可以阻断由次氯酸根阴离子以及乙醛、甲醛和丙二醛（脂质过氧化的主要产物）等有毒醛类诱导的蛋白质-蛋白质和蛋白质-DNA交联。 它还能抑制醛糖和酮糖还原糖诱导的非酶促蛋白糖化，并抑制毒性晚期糖基化终产物（AGE）的形成。这些活性使其被用于对衰老、动脉粥样硬化、阿尔茨海默病和糖尿病的继发性影响的研究。
具有强抗氧化性和抗糖化活性的二肽；阻断由反应性醛诱导的非酶促糖基化和蛋白质交联。
Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
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存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Ok-Nam Bae et al.
Stroke, 44(1), 205-212 (2012-12-20)
An urgent need exists to develop therapies for stroke that have high efficacy, long therapeutic time windows, and acceptable toxicity. We undertook preclinical investigations of a novel therapeutic approach involving supplementation with carnosine, an endogenous pleiotropic dipeptide. Efficacy and safety
Johann Edge et al.
Experimental physiology, 98(2), 481-490 (2012-08-28)
It has been hypothesized that exercise-induced changes in metabolites and ions are crucial in the adaptation of contracting muscle. We tested this hypothesis by comparing adaptations to two different interval-training protocols (differing only in the rest duration between intervals), which
Xue Ming et al.
Journal of proteome research, 11(12), 5856-5862 (2012-10-31)
Autism spectrum disorders (ASD) are a group of biological disorders with associated metabolic derangement. This study aimed to identify a pattern of metabolic perturbance in ASD using metabolomics in urinary specimens from 48 children with ASD and 53 age matched
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| V900370-25G | 04061833462164 |