V900932
D -(+)-海藻糖 二水合物
Vetec™, reagent grade, ≥99%
别名:
D-(+)-海藻糖 二水合物, α,α-海藻糖, α-D-吡喃葡萄糖基-α-D-吡喃葡萄糖苷
等级
reagent grade
产品线
Vetec™
方案
≥99%
表单
powder
储存温度
room temp
SMILES字符串
[H]O[H].[H]O[H].OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
InChI
1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1
InChI key
DPVHGFAJLZWDOC-PVXXTIHASA-N
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相关类别
应用
- 用于局部缓释治疗牙周病的喷雾干燥封装吉非替尼微颗粒。：该研究探讨了如何利用D-(+)-海藻糖二水合物开发喷雾干燥包封吉非替尼微粒，用于牙周病的缓释治疗。该研究强调了这种方法在局部持续给药方面的潜力，可提高疗效并减少全身副作用（Baldelli et al., 2023）。
- 关于可吸入微粒喷雾干燥过程中亮氨酸的颗粒形成。：该研究探讨了在喷雾干燥亮氨酸以制造可吸入微颗粒的过程中颗粒形成的机理。该研究深入探讨了D-(+)-海藻糖二水合物在稳定微粒和改善其气溶胶特性方面的作用，这对开发高效的可吸入微粒至关重要（Ordoubadi et al., 2021）。
法律信息
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
涉药品监管产品
Sabine Ullrich et al.
Journal of pharmaceutical sciences, 104(6), 2040-2046 (2015-04-03)
The importance of cake adhesion to the inside vial wall during lyophilization of amorphous trehalose cakes was determined by using hydrophobized vials. The degrees of cake shrinkage and cracking were determined independently by photographic imaging of the cake top surface
Alan Twomey et al.
International journal of pharmaceutics, 487(1-2), 91-100 (2015-04-19)
In frozen and lyophilized systems, the biological to be stabilized (e.g. therapeutic protein, biomarker, drug-delivery vesicle) and the cryo-/lyo-protectant should be co-localized for successful stabilization. During freezing and drying, many factors cause physical separation of the biological from the cryo-/lyo-protectant
Sabine Ullrich et al.
Pharmaceutical research, 32(8), 2503-2515 (2015-02-06)
Measurement of the kinetic development of shrinkage and cracking of an amorphous trehalose cake as they take place during lyophilization. A novel technique has been developed which monitors a vial in situ during the freeze-drying cycle. The 2-dimensional degrees of
Anke Sass et al.
Drug development and industrial pharmacy, 40(6), 749-757 (2013-04-20)
The spray-drying behaviour of 16 water-miscible organic solvents on a bench-scale machine (Büchi B290 with inert loop) was determined under mild-to-moderate process conditions, namely inlet gas temperature of 130 °C and liquid feed flow rate of ≤3 mL/min. The solvents with boiling
Matthias Erber et al.
International journal of pharmaceutics, 495(2), 692-700 (2015-09-24)
A cryopellet formulation of the diagnostic protein ecarin has been developed that is suitable for use to monitor blood coagulation via in vitro thromboelastometry. The coagulation activity of the ecarin was measured by thromelastometry using whole blood. In aqueous solution
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