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Sadaf Naeem et al.
Bioorganic & medicinal chemistry, 20(3), 1251-1258 (2012-01-21)
Data on phytochemical constituents of plants commonly used in traditional Indonesian medicine have been compiled as a computer database. This database (the Indonesian Herbal constituents database, IHD) currently contains details on ∼1,000 compounds found in 33 different plants. For each
Hee Ju Lee et al.
Journal of agricultural and food chemistry, 62(23), 5290-5295 (2014-05-21)
Hydroxycinnamic acids have antioxidant properties and potentially beneficial effects on human health. This study investigated the digestive stability, bioaccessibility, and permeability of hydroxycinnamic acids from Crepidiastrum denticulatum using simulated digestion and Caco-2 intestinal cells. The major compounds of C. denticulatum
Bo Peng et al.
Molecules (Basel, Switzerland), 18(3), 2934-2941 (2013-03-06)
A high performance liquid chromatography coupled with diode array and evaporative light scattering detection (HPLC-DAD-ELSD) method for simultaneous determination of eight major bioactive compounds including two flavonoids (rutin and eriodictyol-7-O-β-D-glucopyranoside), two isochlorogenic acids (isochlorogenic acid A and isochlorogenic acid C)
Li Zhen Zhang et al.
Food chemistry, 174, 495-501 (2014-12-23)
Commonly consumed foxtail millet varieties Jingu28 and Jingu34 were compared in terms of phytochemical composition, antioxidant property, and antiproliferative activity. The cellular antioxidant activity (CAA) was evaluated based on HepG2 cell cultivation. Antiproliferative properties against HepG2 and MDA cell were
Kui Zeng et al.
Bioorganic & medicinal chemistry letters, 19(18), 5458-5460 (2009-08-14)
Quinic acid (QA) esters found in hot water extracts of Uncaria tomentosa (a.k.a. cat's claw) exert anti-inflammatory activity through mechanisms involving inhibition of the pro-inflammatory transcription factor nuclear factor kappa B (NF-kappaB). Herein, we describe the synthesis and biological testing
Liangmian Chen et al.
Chemical & pharmaceutical bulletin, 63(1), 25-32 (2015-03-07)
For the determination of seven caffeoylquinic acids [neochlorogenic acid (NcA), cryptochlorogenic acid (CcA), chlorogenic acid (CA), caffeic acid (CfA), isochlorogenic acid A (Ic A), isochlorogenic acid B (Ic B), isochlorogenic acid C (Ic C)] and two flavonoids [luteolin 7-O-glucoside (LtG) and luteolin (Lt)]
Jin Mi Chun et al.
BMC complementary and alternative medicine, 14, 234-234 (2014-07-12)
Houttuynia cordata Thunb. (Saururaceae) has been used in traditional medicine for treatment of inflammatory diseases. This study evaluated the anti-inflammatory effects of an ethyl acetate fraction derived from a Houttuynia cordata extract (HCE-EA) on the production of inflammatory mediators and
Alessandra dos Santos Danziger Silvério et al.
Plant foods for human nutrition (Dordrecht, Netherlands), 68(3), 268-273 (2013-06-20)
The effect of coffee on cardiovascular diseases is still controversial. It is known that the process of decaffeination may influence the chemical constitution and, therefore, the biological effects of coffee. This study thus evaluated the effects of decaffeination on the
Chao-Mei Ma et al.
Bioorganic & medicinal chemistry, 18(19), 7009-7014 (2010-09-04)
New derivatives of caffeic acid and quinic acid were synthesized and their anti-fungal and inhibitory activities on fungal 1,3-β-glucan synthase were determined in comparison with those of the corresponding chlorogenic acid derivatives. All the chlorogenic, quinic and caffeic acid derivatives
Zhizhuo Huang et al.
Wei sheng yan jiu = Journal of hygiene research, 37(5), 637-639 (2008-12-17)
Chlorogenic acid (CGA) could be a phenolic acid, which was widely found in food of plant origin and coffee drinks. The studies showed that biological activities of chlorogenic acid could be good for human health. The biological activity of regulating
Maira Huerta-Reyes et al.
Journal of ethnopharmacology, 146(1), 311-317 (2013-01-15)
Heteropterys brachiata is a plant species that has been used in traditional Mexican medicine for the treatment of nervous disorders. To evaluate the anxiolytic, anticonvulsant, antidepressant and sedative effects produced by the methanolic extract of Heteropterys brachiata (HbMeOH) in ICR
P Cremin et al.
Journal of agricultural and food chemistry, 49(4), 1747-1750 (2001-04-20)
Hydroxycinnamates are components of many fruits and vegetables, being present in particularly high concentrations in prunes. An abundance of phenolic compounds in the diet has been associated with reduced heart disease mortality. However, little is known about the absorption and
Spela Može Bornšek et al.
Food chemistry, 173, 61-69 (2014-12-04)
Bilberries processed into spreads represent an important source of anthocyanins if these remain rich in the final product. The effects of thermal processing were studied with non-ground and ground bilberries processed into spreads according to industrial and home-made procedures. Samples
Juan Kang et al.
Biochimica et biophysica acta, 1674(2), 205-214 (2004-09-18)
The interactions of chlorogenic acid and ferulic acid with human serum albumin (HSA) have been investigated by fluorescence and Fourier transformed infrared (FT-IR) spectrometry. Fluorescence results showed that one molecule of protein combined with one molecule of drugs at the
Yanmang Cui et al.
Chemico-biological interactions, 220, 75-83 (2014-06-29)
The study was to characterize the polyphenolic composition, antioxidant properties, and hepatoprotective effects of a polyphenols-enriched extract (HMTP) from Huangshan Maofeng green tea. HPLC analysis showed that three predominantly polyphenolic compounds present in HMTP were epigallocatechin (271.2 μg/mg extract), rutin
What is green coffee extract?
Wendy Marcason
Journal of the Academy of Nutrition and Dietetics, 113(2), 364-364 (2013-01-29)
Shuang Song et al.
Journal of natural products, 73(2), 177-184 (2010-01-23)
Eleven new diglycosides, erycibosides A-K (1-11), four new chlorogenic acid derivatives (14-17), and a new bis-coumarin (18), together with 21 known compounds, have been isolated from an EtOH extract of the roots and stems of Erycibe hainanesis. Their structures were
Jennifer Stella Bonita et al.
Pharmacological research, 55(3), 187-198 (2007-03-21)
Coffee is a commonly consumed beverage with potential health benefits. This review will focus on cardiovascular disease. There are three preparations of coffee that are commonly consumed and thus worthy of examination; boiled unfiltered coffee, filtered coffee, and decaffeinated coffee.
Milton Joseph Ahrens et al.
Journal of medicinal food, 16(3), 211-215 (2013-03-01)
Emulin™ is a patented blend of chlorogenic acid, myricetin, and quercetin that has shown efficacy in reducing midday and post-oral glucose tolerance test (OGTT) area under the curve (AUC) glucose in streptozotocin-treated rats. The purpose of this study was to
Rui-Song Huang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(5), 762-767 (2013-06-04)
To establish quality standard of Zhuang medicine Lonicera dasystyla, and provide scientific basis for the quality control of L. dasystyla. Characteristics of materia medica, microscopic features, TLC indentification, inspection, extractum and determination of chlorogenic acid, macranthoidin B, dipsacoside B were
Yonghui Li et al.
The American journal of Chinese medicine, 41(1), 221-229 (2013-01-23)
In this paper, a useful method for screening and analyzing the potential bioactive components from Reduning Injection was developed using macrophage cell extraction and ultra-high performance liquid chromatography coupled with Q-TOF/MS spectrometry. In addition, the protective effects on macrophage cell
Slawomir Mandziuk et al.
Drug and chemical toxicology, 38(1), 1-8 (2014-03-04)
The delayed cardiomyopathy caused by doxorubicin - an chemotherapeutic drug with broad spectrum of anticancer activity - is mainly triggered by oxidative stress. The aim of this study was to assess an effect of Mutellina purpurea methanolic extract fraction and
Yong Fan et al.
Journal of pharmaceutical and biomedical analysis, 95, 213-219 (2014-04-02)
Sample extraction is the first challenge in analysis of herbal medicines (HMs). Numerous methods have been developed to improve extraction efficiency, use less solvent and short time. In this work, a tissue-smashing based ultra-rapid extraction (TSURE) method has been proposed
Francesco Menichini et al.
Journal of enzyme inhibition and medicinal chemistry, 29(5), 677-685 (2013-10-10)
Cardiospermum halicacabum is widely used in traditional medicine. Previous studies have focused on the aerial parts, while the seeds have been poorly investigated. This work aimed to analyse the chemical composition of extracts from aerial parts and seeds obtained using
Hwa Jung Noh et al.
Journal of nanoscience and nanotechnology, 13(8), 5787-5793 (2013-07-26)
We report the synthesis of biogenic silver nanoparticles using chlorogenic acid as a bioreducing agent. Chlorogenic acid is a polyphenol compound abundant in coffee. UV-Vis spectra showed the characteristic surface plasmon resonance band at 415 nm, indicating the successful synthesis
Janique Vandal et al.
Pharmaceutical biology, 53(6), 800-806 (2015-02-24)
The number of multidrug resistant (MDR) microorganisms is increasing and the antimicrobial resistance expressed by these pathogens is generating a rising global health crisis. In fact, there are only a few antimicrobial agents left that can be used against MDR
Khang Wei Ong et al.
Biochemical pharmacology, 85(9), 1341-1351 (2013-02-19)
Chlorogenic acid (CGA) has been shown to stimulate glucose uptake in skeletal muscle through the activation of AMPK. However, its effect on other metabolic pathways and likewise its effects after long-term consumption have yet to be understood. We investigated the
Roger Fuoco et al.
Journal of plant physiology, 170(7), 668-675 (2013-02-12)
Recently our findings have shown that the integration of the gene coding for the rat gluco-corticoid receptor (GR receptor) in Nicotiana langsdorffii plants induced morphophysiological effects in transgenic plants through the modification of their hormonal pattern. Phytohormones play a key
Sophie Lafay et al.
The British journal of nutrition, 96(1), 39-46 (2006-07-28)
The absorption and metabolism in the small intestine of chlorogenic acid (5-O-caffeoylquinic acid), the main phenolic acid in the human diet, and of caffeic acid were studied in rats in order to determine whether chlorogenic acid is directly absorbed or
R Ejzemberg et al.
Anais da Academia Brasileira de Ciencias, 71(2), 273-277 (1999-07-21)
Previous research on plants used in folk medicine as antidotes against snake-bite revealed some constituents responsible for such protection. Chlorogenic acid (3-0-caffeoyl quinic acid) was one of these substances, studied with more attention. It has been shown that this substance
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